Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR1639] to RAIDD - BSA and Azide free
- Suitable for: WB
- Reacts with: Rat, Human
Product nameAnti-RAIDD antibody [EPR1639] - BSA and Azide free
See all RAIDD primary antibodies
DescriptionRabbit monoclonal [EPR1639] to RAIDD - BSA and Azide free
Tested applicationsSuitable for: WBmore details
Unsuitable for: IHC-P
Species reactivityReacts with: Rat, Human
Synthetic peptide within Human RAIDD aa 100-200. The exact sequence is proprietary.
ab247474 is the carrier-free version of ab76465 This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.
Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.
Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.
Ab247474 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.
Maxpar® is a trademark of Fluidigm Canada Inc.
Mouse: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Storage instructionsShipped at 4°C. Store at +4°C. Do Not Freeze.
Storage bufferpH: 7.2
Concentration information loading...
Our Abpromise guarantee covers the use of ab247474 in the following tested applications.
|WB||Use at an assay dependent concentration. Predicted molecular weight: 23 kDa.|
FunctionApoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex.
Tissue specificityConstitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.
Sequence similaritiesContains 1 CARD domain.
Contains 1 death domain.
DomainContains a death domain involved in the binding of RIP protein.
The CARD domain mediates the interaction with caspase-2.
- Information by UniProt
- CASP2 and RIPK1 domain containing adaptor with death domain antibody
- Caspase and RIP adapter with death domain antibody
- Caspase and RIP adaptor with death domain antibody
All lanes : Anti-RAIDD antibody [EPR1639] (ab76465) at 1/5000 dilution
Lane 1 : Raji cell lysate
Lane 2 : HeLa cell lysate
Lane 3 : K562 cell lysate
Lane 4 : MCF7 cell lysate
Lysates/proteins at 10 µg per lane.
All lanes : goat anti-rabbit HRP at 1/2000 dilution
Predicted band size: 23 kDa
Observed band size: 23 kDa
This data was developed using ab76465, the same antibody clone in a different buffer formulation.
ab247474 has not yet been referenced specifically in any publications.