Anti-RAMP3 antibody (ab78017)
Key features and details
- Rabbit polyclonal to RAMP3
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-RAMP3 antibody
See all RAMP3 primary antibodies -
Description
Rabbit polyclonal to RAMP3 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- IHC-P: Human breast tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab78017 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use a concentration of 20 µg/ml.
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Notes |
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IHC-P
Use a concentration of 20 µg/ml. |
Target
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Relevance
RAMP3 (receptor calcitonin activity modifying protein 3) transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. It acts as a receptor for adrenomedullin (AM) together with CALCRL. It is strongly expressed in lung, breast, immune system and fetal tissues and belongs to the RAMP family. -
Cellular localization
Cell Membrane; Single-pass type I membrane protein -
Database links
- Entrez Gene: 10268 Human
- Omim: 605155 Human
- SwissProt: O60896 Human
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Alternative names
- Calcitonin receptor like receptor activity modifying protein 3 antibody
- CRLR activity modifying protein 3 antibody
- CRLR activity-modifying protein 3 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab78017 has been referenced in 2 publications.
- Wu X et al. IAPP modulates cellular autophagy, apoptosis, and extracellular matrix metabolism in human intervertebral disc cells. Cell Death Discov 3:16107 (2017). PubMed: 28149534
- Fu W et al. Role of microglial amylin receptors in mediating beta amyloid (Aß)-induced inflammation. J Neuroinflammation 14:199 (2017). PubMed: 28985759