• Product name

  • Description

    Rabbit polyclonal to Ran
  • Host species

  • Specificity

    Observed cross-reactivity with ~26 kDa tag.
  • Tested applications

    Suitable for: WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Saccharomyces cerevisiae
  • Immunogen

    Recombinant fusion protein (S. cerevisiae).



Our Abpromise guarantee covers the use of ab11693 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Detects a band of approximately 25 kDa (predicted molecular weight: 26 kDa).
ICC/IF Use at an assay dependent dilution.


  • Function

    GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules.
    Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.
  • Tissue specificity

    Expressed in a variety of tissues.
  • Sequence similarities

    Belongs to the small GTPase superfamily. Ran family.
  • Post-translational

    The N-terminus is blocked.
  • Cellular localization

    Nucleus. Cytoplasm. Melanosome. Becomes dispersed throughout the cytoplasm during mitosis. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • Alternative names

    • Androgen receptor associated protein 24 antibody
    • Androgen receptor-associated protein 24 antibody
    • ARA 24 antibody
    • ARA24 antibody
    • Gsp1 antibody
    • GTP binding nuclear protein RAN antibody
    • GTP-binding nuclear protein Ran antibody
    • GTPase Ran antibody
    • Guanosine triphosphatase Ran antibody
    • LPS antibody
    • OK/SW-cl.81 antibody
    • ran antibody
    • RAN member RAS oncogene family antibody
    • RAN_HUMAN antibody
    • RanGTPase antibody
    • Ras like protein TC4 antibody
    • Ras related nuclear protein antibody
    • Ras-like protein TC4 antibody
    • Ras-related nuclear protein antibody
    • RASL2 8 antibody
    • TC 4 antibody
    • TC4 antibody
    see all


  • ab11693 at a 1/1000 dilution staining approximately 25kDa Ran in S.cerevisiae whole cell lysate by Western blot (ECL). ab11693 at a 1/1000 dilution staining approximately 25kDa Ran in S.cerevisiae whole cell lysate by Western blot (ECL).


This product has been referenced in:

  • Roubinet C  et al. Spatio-temporally separated cortical flows and spindle geometry establish physical asymmetry in fly neural stem cells. Nat Commun 8:1383 (2017). Read more (PubMed: 29123099) »
  • Sun J  et al. Dendrobium candidum inhibits MCF-7 cells proliferation by inducing cell cycle arrest at G2/M phase and regulating key biomarkers. Onco Targets Ther 9:21-30 (2016). WB ; Human . Read more (PubMed: 26730200) »
See all 3 Publications for this product

Customer reviews and Q&As


Thank you for contacting us. Unfortunately, other than ab11693 which cross-reacts with the 26 kDa tag, our other Ran antibodies are raised against human Ran. Most would be unlikely to cross-react with yeast, due to low sequence homology with their immunogens, but ab4781 may be suitable. This antibody is a rabbit polyclonal raised against the full length human sequence (His-tagged), which shows 83% homology with yeast. If you would like to try this antibody, I would be happy to send it to you as a free of charge replacement. Please let me know your original order number and how you would like to proceed and I will be happy to help you further.

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