Overview

  • Product name

  • Description

    Rabbit polyclonal to Ran
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Zebrafish
    Predicted to work with: Mouse, Rat, Cow, Human
  • Immunogen

    Recombinant fragment within Zebrafish Ran aa 2-215. The exact sequence is proprietary.
    Database link: P79735

  • Positive control

    • Whole Zebrafish cell lysate, Zebrafish tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab209725 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/1000.
WB 1/500 - 1/3000. Predicted molecular weight: 24 kDa.

Target

  • Function

    GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules.
    Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.
  • Tissue specificity

    Expressed in a variety of tissues.
  • Sequence similarities

    Belongs to the small GTPase superfamily. Ran family.
  • Post-translational
    modifications

    The N-terminus is blocked.
  • Cellular localization

    Nucleus. Cytoplasm. Melanosome. Becomes dispersed throughout the cytoplasm during mitosis. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • Database links

  • Alternative names

    • Androgen receptor associated protein 24 antibody
    • Androgen receptor-associated protein 24 antibody
    • ARA 24 antibody
    • ARA24 antibody
    • Gsp1 antibody
    • GTP binding nuclear protein RAN antibody
    • GTP-binding nuclear protein Ran antibody
    • GTPase Ran antibody
    • Guanosine triphosphatase Ran antibody
    • LPS antibody
    • OK/SW-cl.81 antibody
    • ran antibody
    • RAN member RAS oncogene family antibody
    • RAN_HUMAN antibody
    • RanGTPase antibody
    • Ras like protein TC4 antibody
    • Ras related nuclear protein antibody
    • Ras-like protein TC4 antibody
    • Ras-related nuclear protein antibody
    • RASL2 8 antibody
    • TC 4 antibody
    • TC4 antibody
    see all

Images

  • Anti-Ran antibody (ab209725) at 1/1000 dilution + Zebrafish whole cell lysate at 30 µg

    Predicted band size: 24 kDa



    12% SDS-PAGE

  • Immunohistochemical analysis of formalin fixed paraffin embedded Zebrafish tissue section labeling Ran with ab209725 at 1/300

References

ab209725 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab209725.
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