Overview

  • Product name

  • Description

    Rabbit polyclonal to RanBP1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide within Human RanBP1 aa 86-116 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    IRLLMRRDKTLKICANHYITPMMELKPNAGS


    Database link: P43487

  • Positive control

    • Human rectal carcinoma tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab217940 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.

Target

  • Function

    Inhibits GTP exchange on Ran. Forms a Ran-GTP-RANBP1 trimeric complex. Increase GTP hydrolysis induced by the Ran GTPase activating protein RANGAP1. May act in an intracellular signaling pathway which may control the progression through the cell cycle by regulating the transport of protein and nucleic acids across the nuclear membrane.
  • Sequence similarities

    Belongs to the RANBP1 family.
    Contains 1 RanBD1 domain.
  • Information by UniProt
  • Database links

  • Alternative names

    • HTF9A antibody
    • RAN binding protein 1 antibody
    • Ran specific GTPase activating protein antibody
    • Ran-binding protein 1 antibody
    • Ran-specific GTPase-activating protein antibody
    • RANBP1 antibody
    • RANG_HUMAN antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed and paraffin embedded Human rectal carcinoma tissue labeling RanBP1 using ab217940 at 1/200, followed by secondary detection and DAB staining.

References

ab217940 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab217940.
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