Key features and details
- Rabbit polyclonal to RAP1A
- Suitable for: WB
- Reacts with: Mouse, Rat, Rabbit, Guinea pig, Cow, Dog, Human
- Isotype: IgG
Product nameAnti-RAP1A antibody
See all RAP1A primary antibodies
DescriptionRabbit polyclonal to RAP1A
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Rat, Rabbit, Guinea pig, Cow, Dog, Human
Synthetic peptide corresponding to a sequence near the C terminus of Human, mouse and Rat RAP1A.
- Rat and Mouse brain tissue extracts.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at -20ºC.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 49% PBS, 50% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab115776 is peptide immunoaffinity purified.
Our Abpromise guarantee covers the use of ab115776 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000. Detects a band of approximately 25 kDa (predicted molecular weight: 21 kDa).|
FunctionInduces morphological reversion of a cell line transformed by a Ras oncogene. Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner.
Sequence similaritiesBelongs to the small GTPase superfamily. Ras family.
Cellular localizationCell membrane.
- Information by UniProt
- C21KG antibody
- G 22K antibody
- G-22K antibody
ab115776 has been referenced in 2 publications.
- Volovetz J et al. Identifying conserved molecular targets required for cell migration of glioblastoma cancer stem cells. Cell Death Dis 11:152 (2020). PubMed: 32102991
- Yao R et al. miR-142-5p regulates pancreatic cancer cell proliferation and apoptosis by regulation of RAP1A. Pathol Res Pract N/A:152416 (2019). PubMed: 31047726