Overview

  • Product name
  • Description
    Rabbit polyclonal to RAP1GDS1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human RAP1GDS1 (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Sequence:

    IAEELVKLFKKQIEHDKREMIFEVLAPLA


    Database link: P52306

  • Positive control
    • HepG2 and MDA-MB231 cell lysates, Human brain tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab170358 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/10 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/100 - 1/500. Predicted molecular weight: 66 kDa.

Target

  • Function
    Stimulates GDP/GTP exchange reaction of a group of small GTP-binding proteins (G proteins) including Rap1a/Rap1b, RhoA, RhoB and KRas, by stimulating the dissociation of GDP from and the subsequent binding of GTP to each small G protein.
  • Sequence similarities
    Contains 5 ARM repeats.
  • Information by UniProt
  • Database links
  • Alternative names
    • Exchange factor smgGDS antibody
    • GDP dissociation stimulator 1 antibody
    • GDS1 antibody
    • GDS1_HUMAN antibody
    • GTP-GDP dissociation stimulator 1 antibody
    • GTPase-GDP dissociation stimulator, Rap1, 1 antibody
    • Highly similar to RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1 antibody
    • MGC118859 antibody
    • MGC118861 antibody
    • RAP1 antibody
    • Rap1 GTPase-GDP dissociation stimulator 1 antibody
    • RAP1GDS1 antibody
    • SMG GDS protein antibody
    • SMG P21 stimulatory GDP/GTP exchange protein antibody
    • SMGGDS antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed paraffin-embedded Human brain tissue, labeling RAP1GDS1 using ab170358 at a 1/50 dilution, followed by peroxidase conjugation of the secondary antibody and DAB staining.

  • All lanes : Anti-RAP1GDS1 antibody (ab170358) at 1/100 dilution

    Lane 1 : HepG2 cell lysate
    Lane 2 : MDA-MB231 cell lysate

    Lysates/proteins at 35 µg per lane.

    Predicted band size: 66 kDa

References

ab170358 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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