Key features and details
- Rabbit polyclonal to RAP2B
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-RAP2B antibody
See all RAP2B primary antibodies
DescriptionRabbit polyclonal to RAP2B
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Pig, Orangutan
Recombinant full length protein corresponding to Human RAP2B aa 1-183.
MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSP SVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQI IRVKRYERVPMILVGNKVDLEGEREVSYGEGKALAEEWSCPFMETSAKNK ASVDELFAEIVRQMNYAAQPNGDEGCCSACVIL
Database link: P61225
- IHC-P: Human brain and kidney tissue.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab234791 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/20 - 1/200.|
FunctionSmall GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. Involved in EGFR and CHRM3 signaling pathways through stimulation of PLCE1. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May regulate membrane vesiculation in red blood cells.
Tissue specificityExpressed in red blood cells (at protein level).
Sequence similaritiesBelongs to the small GTPase superfamily. Ras family.
DomainThe effector domain mediates the interaction with RUNDC3A.
modificationsPalmitoylated. Palmitoylation is required for association with recycling endosome membranes and activation of TNIK.
Cellular localizationRecycling endosome membrane. Associated with red blood cells-released vesicles.
- Information by UniProt
- MGC20484 antibody
- RAP 2B antibody
- RAP2A antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab234791 has not yet been referenced specifically in any publications.