Key features and details
- Rabbit polyclonal to RARS2
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-RARS2 antibody
DescriptionRabbit polyclonal to RARS2
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Human
Predicted to work with: Cow, Orangutan
Recombinant fragment corresponding to Human RARS2 aa 17-340.
LNLPPENLITSISAVPISQKEEVADFQLSVDSLLEKDNDHSRPDIQVQAK RLAEKLRCDTVVSEISTGQRTVNFKINRELLTKTVLQQVIEDGSKYGLKS ELFSGLPQKKIVVEFSSPNVAKKFHVGHLRSTIIGNFIANLKEALGHQVI RINYLGDWGMQFGLLGTGFQLFGYEEKLQSNPLQHLFEVYVQVNKEAADD KSVAKAAQEFFQRLELGDVQALSLWQKFRDLSIEEYIRVYKRLGVYFDEY SGESFYREKSQEVLKLLESKGLLLKTIKGTAVVDLSGNGDPSSICTVMRS DGTSLYATRDLAAAIDRMDKYNFD
Database link: Q5T160
- WB: Mouse kidney tissue lysate and HL-60 whole cell lysate. IHC-P: Human lung cancer and gastric cancer tissue.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab230274 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/20 - 1/200.|
|WB||1/1000 - 1/5000. Detects a band of approximately 66 kDa (predicted molecular weight: 66 kDa).|
Involvement in diseaseDefects in RARS2 are the cause of pontocerebellar hypoplasia type 6 (PCH6) [MIM:611523]; also known as fatal infantile encephalopathy with mitochondrial respiratory chain defects. Pontocerebellar hypoplasia (PCH) is a heterogeneous group of disorders characterized by an abnormally small cerebellum and brainstem.
Sequence similaritiesBelongs to the class-I aminoacyl-tRNA synthetase family.
Cellular localizationMitochondrion matrix.
- Information by UniProt
- arginine tRNA ligase antibody
- arginyl tRNA synthetase 2 mitochondrial antibody
- Arginyl tRNA synthetase antibody
All lanes : Anti-RARS2 antibody (ab230274) at 1/1000 dilution
Lane 1 : Mouse kidney tissue lysate
Lane 2 : HL-60 (Human promyelocytic leukemia cell line) whole cell lysate
All lanes : Goat polyclonal to rabbit IgG at 1/10000 dilution
Developed using the ECL technique.
Predicted band size: 66 kDa
Observed band size: 66 kDa
Paraffin-embedded human lung cancer tissue stained for RARS2 with ab230274 at 1/100 dilution in immunohistochemical analysis.
Paraffin-embedded human gastric cancer tissue stained for RARS2 with ab230274 at 1/100 dilution in immunohistochemical analysis.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab230274 has not yet been referenced specifically in any publications.