Overview

  • Product name

  • Description

    Mouse polyclonal to RASAL1
  • Host species

    Mouse
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Full length protein corresponding to amino acids 1-776 of Human RASAL1, Isoform 2 (AAH14420.1)

  • Positive control

    • WB: 293T cells transfected with RASAL1.

Properties

Applications

Our Abpromise guarantee covers the use of ab168610 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 90 kDa.

Target

  • Function

    Probable inhibitory regulator of the Ras-cyclic AMP pathway.
  • Tissue specificity

    Highly expressed in thyroid and adrenal medulla, lower expression in brain, spinal cord and trachea.
  • Sequence similarities

    Contains 1 Btk-type zinc finger.
    Contains 2 C2 domains.
    Contains 1 PH domain.
    Contains 1 Ras-GAP domain.
  • Information by UniProt
  • Database links

  • Form

    It localizes to cytoplasm.
  • Alternative names

    • GAP1 like protein antibody
    • MRASAL antibody
    • RAS GTPase activating protein like antibody
    • RAS protein activator like 1 (GAP1 like) antibody
    • RAS protein activator like 1 antibody
    • RASAL antibody
    • Rasal1 antibody
    • rasGAP activating like protein 1 antibody
    • RasGAP-activating-like protein 1 antibody
    • RASGAP1 LIKE antibody
    • RASL1_HUMAN antibody
    see all

Images

  • All lanes : Anti-RASAL1 antibody (ab168610) at 1 µg/ml

    Lane 1 : Lysates of 293T cells transfected with RASAL1 (85.36 KDa)
    Lane 2 : Lysates of untransfected 293T cells

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 90 kDa

References

This product has been referenced in:

  • Xu X  et al. High-fidelity CRISPR/Cas9- based gene-specific hydroxymethylation rescues gene expression and attenuates renal fibrosis. Nat Commun 9:3509 (2018). Read more (PubMed: 30158531) »
  • McDonnell F  et al. Hypoxia-Induced Changes in DNA Methylation Alter RASAL1 and TGFß1 Expression in Human Trabecular Meshwork Cells. PLoS One 11:e0153354 (2016). Read more (PubMed: 27124111) »
See all 2 Publications for this product

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