Overview

  • Product name

    Rat Muscarinic Acetylcholine Receptor M3/CHRM3 peptide

Description

  • Nature

    Recombinant
  • Amino Acid Sequence
    • Accession
    • Species

      Rat
    • Additional sequence information

      Within residues 500 to the C-terminus of Rat Muscarinic Acetylcholine Receptor M3.

Specifications

Our Abpromise guarantee covers the use of ab139964 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

  • Purity

    70 - 90% by HPLC.

  • Form

    Liquid
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

     This product was previously labelled as Muscarinic Acetylcholine Receptor M3

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names

    • AChR
    • ACM3_HUMAN
    • cholinergic receptor muscarinic 3
    • CHRM 3
    • CHRM3
    • EGBRS
    • HM 3
    • HM3
    • m3 muscarinic acetylcholine receptor
    • M3 muscarinic receptor
    • muscarinic 3
    • Muscarinic acetylcholine receptor M3
    • muscarinic cholinergic m3 receptor
    • muscarinic m3 receptor
    see all
  • Function

    The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM3 sub-subfamily.
  • Cellular localization

    Cell membrane. Cell junction > synapse > postsynaptic cell membrane. Basolateral cell membrane.
  • Information by UniProt

References

ab139964 has not yet been referenced specifically in any publications.

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