Anti-RB associated KRAB repressor antibody (ab72609)
Key features and details
- Rabbit polyclonal to RB associated KRAB repressor
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-RB associated KRAB repressor antibody
See all RB associated KRAB repressor primary antibodies -
Description
Rabbit polyclonal to RB associated KRAB repressor -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse -
Immunogen
A synthesized peptide derived from N-terminal of human RB associated KRAB repressor.
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Positive control
- Extracts from HepG2 cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab72609 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/1000. Detects a band of approximately 85 kDa (predicted molecular weight: 83 kDa).
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Notes |
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WB
1/500 - 1/1000. Detects a band of approximately 85 kDa (predicted molecular weight: 83 kDa). |
Target
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Function
May repress E2F-dependent transcription. May promote AR-dependent transcription. -
Tissue specificity
Expressed in bone, brain, heart, kidney, liver, lung, pancreas and placenta. -
Sequence similarities
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 16 C2H2-type zinc fingers.
Contains 1 KRAB domain. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 57786 Human
- Entrez Gene: 57782 Mouse
- Omim: 608191 Mouse
- SwissProt: Q9NYW8 Human
- SwissProt: Q8BQC8 Mouse
- Unigene: 396178 Human
- Unigene: 320419 Mouse
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Alternative names
- hRBaK antibody
- Hypothetical protein RBAK antibody
- RB associated KRAB zinc finger antibody
see all
Images
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All lanes : Anti-RB associated KRAB repressor antibody (ab72609) at 1/500 dilution
Lane 1 : Extracts from HepG2 cells
Lane 2 : Extracts from HepG2 cells plus 5µg immunizing peptide
Lysates/proteins at 5 µg per lane.
Predicted band size: 83 kDa
Observed band size: 85 kDa why is the actual band size different from the predicted?
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab72609 has been referenced in 1 publication.
- Gutekunst CA et al. C3 transferase gene therapy for continuous conditional RhoA inhibition. Neuroscience 339:308-318 (2016). PubMed: 27746349