• Product name

  • Description

    Rabbit polyclonal to RBM10/S1-1
  • Host species

  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to Human RBM10/S1-1 aa 74-123 (N terminal).


  • Positive control

    • Daudi cell lysate. Human heart or lung sections.
  • General notes

    Protein previously labeled as RBM10.



Our Abpromise guarantee covers the use of ab26046 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
WB Use a concentration of 1.4 µg/ml. Predicted molecular weight: 104 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • Function

    May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A).
  • Involvement in disease

    Defects in RBM10 are the cause of TARP syndrome (TARPS) [MIM:311900]. It is a disorder characterized by the Robin sequence (micrognathia, glossoptosis and cleft palate), talipes equinovarus and cardiac defects.
  • Sequence similarities

    Contains 1 C2H2-type zinc finger.
    Contains 1 G-patch domain.
    Contains 1 RanBP2-type zinc finger.
    Contains 2 RRM (RNA recognition motif) domains.
  • Post-translational

    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization

    Nucleus. In the extranucleolar nucleoplasm constitutes hundreds of nuclear domains, which dynamically change their structures in a reversible manner. Upon globally reducing RNA polymerase II transcription, the nuclear bodies enlarge and decrease in number. They occur closely adjacent to nuclear speckles or IGCs (interchromatin granule clusters) but coincide with TIDRs.
  • Information by UniProt
  • Database links

  • Alternative names

    • DXS8237E antibody
    • G patch domain containing protein 9 antibody
    • G patch domain-containing protein 9 antibody
    • GPATC9 antibody
    • GPATCH9 antibody
    • HGNC9896 antibody
    • KIAA0122 antibody
    • MGC1132 antibody
    • MGC997 antibody
    • Rbm10 antibody
    • RBM10_HUMAN antibody
    • RNA binding motif protein 10 antibody
    • RNA binding protein 10 antibody
    • RNA binding protein S1-1 antibody
    • RNA-binding motif protein 10 antibody
    • RNA-binding protein 10 antibody
    • RNA-binding protein S1-1 antibody
    • S1-1 antibody
    • TARPS antibody
    • ZRANB5 antibody
    see all


  • Anti-RBM10/S1-1 antibody (ab26046) at 0.5 µg/ml + Daudi cell lysate

    HRP conjugated anti-Rabbit IgG diluted 1: 50,000 - 100,000

    Predicted band size: 104 kDa

  • Staining of human heart tissue with ab26046 at a 4.0-8.0ug/ml dilution. Positive labelled myocardial cells are indicated with arrows.
  • Staining of human lung tissue with ab26046 at a 4.0-8.0ug/ml dilution. Positive labelled epithelial cells of bronchiole are indicated with arrows.


This product has been referenced in:

  • Guan G  et al. Expression of RNA-binding motif 10 is associated with advanced tumor stage and malignant behaviors of lung adenocarcinoma cancer cells. Tumour Biol 39:1010428317691740 (2017). Read more (PubMed: 28347232) »
  • Ji Y  et al. Increased cell apoptosis in human lung adenocarcinoma andin vivotumor growth inhibition byRBM10, a tumor suppressor gene. Oncol Lett 14:4663-4669 (2017). Read more (PubMed: 29085465) »
See all 3 Publications for this product

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