Anti-RBM38 antibody (ab168445)
- Datasheet
- References
- Protocols
Overview
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Product nameAnti-RBM38 antibody
See all RBM38 primary antibodies -
DescriptionMouse polyclonal to RBM38
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Host speciesMouse
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Tested applicationsSuitable for: WBmore details
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Species reactivityReacts with: Human
Predicted to work with: Mouse
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Immunogen
Recombinant full length protein corresponding to amino acids 1-239 of Human RBM38. (NP_05965.2).
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Positive control
- Transfected 293T cell lysate.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
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Storage bufferpH: 7.20
Constituent: 100% PBS -
Concentration information loading... -
PurityProtein A purified
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab168445 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use a concentration of 1 µg/ml. Detects a band of approximately 26.29 kDa. |
Target
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FunctionRNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.
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Sequence similaritiesBelongs to the RBM38 family.
Contains 1 RRM (RNA recognition motif) domain. -
Cellular localizationCytoplasm, cytosol. Nucleus.
- Information by UniProt
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Database links
- Entrez Gene: 55544 Human
- Entrez Gene: 56190 Mouse
- Omim: 612428 Human
- SwissProt: Q9H0Z9 Human
- SwissProt: Q62176 Mouse
- Unigene: 236361 Human
- Unigene: 485782 Mouse
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Alternative names
- CLL associated antigen KW 5 antibody
- CLL-associated antigen KW-5 antibody
- HSRNASEB antibody
see all
Images
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Western blot - Anti-RBM38 antibody (ab168445)All lanes : Anti-RBM38 antibody (ab168445) at 1 µg/ml
Lane 1 : Transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 50 µg per lane.
Secondary
All lanes : Goat Anti-mouse HRP at 1/2500 dilution
Protocols
Datasheets and documents
References
ab168445 has not yet been referenced specifically in any publications.
