Anti-RBM38 antibody (ab168445)

Submit a review Submit a question
Western blot - Anti-RBM38 antibody (ab168445)

    Key features and details

    • Mouse polyclonal to RBM38
    • Suitable for: WB
    • Reacts with: Human
    • Isotype: IgG

    Overview

    • Product name

      Anti-RBM38 antibody
      See all RBM38 primary antibodies

    • Description

      Mouse polyclonal to RBM38

    • Host species

      Mouse

    • Tested applications

      Suitable for: WBmore details

    • Species reactivity

      Reacts with: Human
      Predicted to work with: Mouse

    • Immunogen

      Recombinant full length protein corresponding to amino acids 1-239 of Human RBM38. (NP_05965.2).

      Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

    • Positive control

      • Transfected 293T cell lysate.

    • General notes

      Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

      Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

      We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

      In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

      We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

      Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

      Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

    Properties

    Applications

    Our Abpromise guarantee covers the use of ab168445 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    WB Use a concentration of 1 µg/ml. Detects a band of approximately 26.29 kDa.

    Target

    • Function

      RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.

    • Sequence similarities

      Belongs to the RBM38 family.
      Contains 1 RRM (RNA recognition motif) domain.

    • Cellular localization

      Cytoplasm, cytosol. Nucleus.
    • Information by UniProt

    • Database links

      • Alternative names

        • CLL associated antigen KW 5 antibody
        • CLL-associated antigen KW-5 antibody
        • HSRNASEB antibody
        • RBM38 antibody
        • RBM38_HUMAN antibody
        • RNA binding motif protein 38 antibody
        • RNA binding protein 38 antibody
        • RNA binding region (RNP1, RRM) containing 1 antibody
        • RNA binding region containing protein 1 antibody
        • RNA-binding motif protein 38 antibody
        • RNA-binding protein 38 antibody
        • RNA-binding region-containing protein 1 antibody
        • RNPC1 antibody
        • SEB4 antibody
        • SEB4B antibody
        • SEB4D antibody
        • ssDNA binding protein SEB4 antibody
        • ssDNA-binding protein SEB4 antibody
        see all

      Images

      • Western blot - Anti-RBM38 antibody (ab168445)
        Western blot - Anti-RBM38 antibody (ab168445)
        All lanes : Anti-RBM38 antibody (ab168445) at 1 µg/ml

        Lane 1 : Transfected 293T cell lysate
        Lane 2 : Non-transfected 293T cell lysate

        Lysates/proteins at 50 µg per lane.

        Secondary
        All lanes : Goat Anti-mouse HRP at 1/2500 dilution

      References (0)

      Publishing research using ab168445? Please let us know so that we can cite the reference in this datasheet.

      ab168445 has not yet been referenced specifically in any publications.

      Customer reviews and Q&As

      Show All Reviews Q&A
      Submit a review Submit a question

      There are currently no Customer reviews or Questions for ab168445.
      Please use the links above to contact us or submit feedback about this product.

      Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
      For licensing inquiries, please contact partnerships@abcam.com