• Product name

  • Description

    Rabbit polyclonal to RBM38
  • Host species

  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Guinea pig, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within internal amino acids 190-239 (YPYAASPATA ASFVGYSYPA AVPQALSAAA PAGTTFVQYQ APQLQPDRMQ) of human RBM38 (NP_059965).

  • Positive control

    • HT1080 cell lysate



Our Abpromise guarantee covers the use of ab94420 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 25 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • Function

    RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.
  • Sequence similarities

    Belongs to the RBM38 family.
    Contains 1 RRM (RNA recognition motif) domain.
  • Cellular localization

    Cytoplasm, cytosol. Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • CLL associated antigen KW 5 antibody
    • CLL-associated antigen KW-5 antibody
    • HSRNASEB antibody
    • RBM38 antibody
    • RBM38_HUMAN antibody
    • RNA binding motif protein 38 antibody
    • RNA binding protein 38 antibody
    • RNA binding region (RNP1, RRM) containing 1 antibody
    • RNA binding region containing protein 1 antibody
    • RNA-binding motif protein 38 antibody
    • RNA-binding protein 38 antibody
    • RNA-binding region-containing protein 1 antibody
    • RNPC1 antibody
    • SEB4 antibody
    • SEB4B antibody
    • SEB4D antibody
    • ssDNA binding protein SEB4 antibody
    • ssDNA-binding protein SEB4 antibody
    see all


  • Anti-RBM38 antibody (ab94420) at 1 µg/ml (in 5% skim milk / PBS buffer ) + HT1080 cell lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size: 25 kDa

    Gel concentration: 12%


This product has been referenced in:

  • Ding C  et al. Long non-coding RNA HOTAIR promotes cell migration and invasion via down-regulation of RNA binding motif protein 38 in hepatocellular carcinoma cells. Int J Mol Sci 15:4060-76 (2014). WB ; Human . Read more (PubMed: 24663081) »
See 1 Publication for this product

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