Recombinant Anti-RBMS1 antibody [EPR9825(B)] (ab150353)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR9825(B)] to RBMS1
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
Related conjugates and formulations
Overview
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Product name
Anti-RBMS1 antibody [EPR9825(B)]
See all RBMS1 primary antibodies -
Description
Rabbit monoclonal [EPR9825(B)] to RBMS1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details
Unsuitable for: Flow Cyt,ICC/IF or IHC-P -
Species reactivity
Reacts with: Mouse, Rat, Human -
Immunogen
Synthetic peptide within Human RBMS1 aa 350-450 (C terminal). The exact sequence is proprietary.
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Positive control
- HeLa, HepG2, Jurkat, C6, Raw 264.7 and NIH3T3 cell lysates
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20ºC. -
Storage buffer
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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Purity
Tissue culture supernatant -
Clonality
Monoclonal -
Clone number
EPR9825(B) -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab150353 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/1000 - 1/10000. Predicted molecular weight: 45 kDa.
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Notes |
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WB
1/1000 - 1/10000. Predicted molecular weight: 45 kDa. |
Target
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Function
Single-stranded DNA binding protein that interacts with the region upstream of the MYC gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication. -
Tissue specificity
Highest amounts are found in placenta, lung and heart. -
Sequence similarities
Contains 2 RRM (RNA recognition motif) domains. -
Developmental stage
Expressed at highest levels during the G1 to S transition of the cell cycle. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 5937 Human
- Entrez Gene: 56878 Mouse
- Entrez Gene: 362138 Rat
- GenBank: NP_058520.1 Human
- Omim: 602310 Human
- SwissProt: P29558 Human
- SwissProt: Q91W59 Mouse
- SwissProt: Q5PQP1 Rat
see all -
Alternative names
- c myc gene single strand binding protein 2 antibody
- C2orf12 antibody
- Cervical cancer oncogene 4 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab150353 has been referenced in 3 publications.
- Zhang J et al. Loss of RBMS1 promotes anti-tumor immunity through enabling PD-L1 checkpoint blockade in triple-negative breast cancer. Cell Death Differ 29:2247-2261 (2022). PubMed: 35538152
- Hoefig KP et al. Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation. Nat Commun 12:5208 (2021). PubMed: 34471108
- Leppek K & Stoecklin G An optimized streptavidin-binding RNA aptamer for purification of ribonucleoprotein complexes identifies novel ARE-binding proteins. Nucleic Acids Res N/A:N/A (2013). WB, IP ; Human . PubMed: 24157833