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  1. Link

    rbp4-antibody-ab231587.pdf

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Cardiovascular Blood Serum Proteins
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Anti-RBP4 antibody (ab231587)

  • Datasheet
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  • Western blot - Anti-RBP4 antibody (ab231587)
  • Western blot - Anti-RBP4 antibody (ab231587)
  • Western blot - Anti-RBP4 antibody (ab231587)
  • Western blot - Anti-RBP4 antibody (ab231587)

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  • Datasheet
  • References
  • Protocols

Overview

  • Product name

    Anti-RBP4 antibody
    See all RBP4 primary antibodies
  • Description

    Rabbit polyclonal to RBP4
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Cow, Pig
    Predicted to work with: Rabbit, Horse, Cat, Human, Chimpanzee
  • Immunogen

    Recombinant fragment (His-tag) corresponding to Pig RBP4 aa 19-201. (Expressed in E.coli)
    Sequence:

    ERDCRVSSFRVKENFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDEN GHMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKG NDDHWIIDTDYDTYAVQYSCRLQNLDGTCADSYSFVFARDPHGFSPEVQK IVRQRQEELCLARQYRIITHNGYCDGKSERNIL


    Database link: P27485

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive control

    • WB: Recombinant pig RBP4 protein; Cow liver lysate; Pig serum and liver lysate.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.4
    Preservative: 0.02% Sodium azide
    Constituents: PBS, 50% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    Antigen-specific affinity chromatography followed by Protein A affinity chromatography.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Cardiovascular
    • Blood
    • Serum Proteins
    • Signal Transduction
    • Metabolism
    • Vitamins / Minerals
    • Cardiovascular
    • Atherosclerosis
    • Diabetes associated
    • Metabolism
    • Pathways and Processes
    • Cofactors, Vitamins / minerals
    • Vitamins / minerals
    • Metabolism
    • Types of disease
    • Diabetes
    • Metabolism
    • Types of disease
    • Heart disease

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
  • Recombinant Protein

    • Recombinant Human RBP4 protein (ab63267)

Applications

Our Abpromise guarantee covers the use of ab231587 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.2 - 2 µg/ml. Predicted molecular weight: 23 kDa.

Target

  • Function

    Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.
  • Involvement in disease

    Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:180250]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium.
  • Sequence similarities

    Belongs to the calycin superfamily. Lipocalin family.
  • Cellular localization

    Secreted.
  • Target information above from: UniProt accession P02753 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 450617 Chimpanzee
    • Entrez Gene: 281444 Cow
    • Entrez Gene: 100049790 Horse
    • Entrez Gene: 5950 Human
    • Entrez Gene: 397124 Pig
    • Entrez Gene: 100009161 Rabbit
    • Omim: 180250 Human
    • SwissProt: M5AXY1 Cat
    • SwissProt: P61641 Chimpanzee
    • SwissProt: P18902 Cow
    • SwissProt: Q28369 Horse
    • SwissProt: P02753 Human
    • SwissProt: P27485 Pig
    • SwissProt: P06912 Rabbit
    • Unigene: 50223 Human
    see all
  • Alternative names

    • OTTHUMP00000020114 antibody
    • OTTHUMP00000020115 antibody
    • OTTHUMP00000020116 antibody
    • Plasma retinol binding protein 4 antibody
    • Plasma retinol-binding protein antibody
    • Plasma retinol-binding protein(1-176) antibody
    • PRBP antibody
    • PRO2222 antibody
    • RBP antibody
    • RBP4 antibody
    • RDCCAS antibody
    • RET4_HUMAN antibody
    • Retinol binding protein 4 antibody
    • Retinol binding protein 4 interstitial antibody
    • Retinol binding protein 4 plasma antibody
    see all

Images

  • Western blot - Anti-RBP4 antibody (ab231587)
    Western blot - Anti-RBP4 antibody (ab231587)
    Anti-RBP4 antibody (ab231587) at 2 µg/ml + Pig liver lysate.

    Predicted band size: 23 kDa

  • Western blot - Anti-RBP4 antibody (ab231587)
    Western blot - Anti-RBP4 antibody (ab231587)
    Anti-RBP4 antibody (ab231587) at 1 µg/ml + Pig serum.

    Developed using the ECL technique.

    Predicted band size: 23 kDa

  • Western blot - Anti-RBP4 antibody (ab231587)
    Western blot - Anti-RBP4 antibody (ab231587)
    Anti-RBP4 antibody (ab231587) at 2 µg/ml + Cow liver lysate.

    Developed using the ECL technique.

    Predicted band size: 23 kDa

  • Western blot - Anti-RBP4 antibody (ab231587)
    Western blot - Anti-RBP4 antibody (ab231587)
    Anti-RBP4 antibody (ab231587) at 2 µg/ml + Recombinant pig RBP4 protein.

    Developed using the ECL technique.

    Predicted band size: 23 kDa

Datasheets and documents

    • Datasheet
  • References

    ab231587 has not yet been referenced specifically in any publications.

    Publishing research using ab231587? Please let us know so that we can cite the reference in this datasheet.

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