Anti-RECK antibody [MM0523-9G19] (ab89915)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-RECK antibody [MM0523-9G19]
See all RECK primary antibodies -
Description
Mouse monoclonal [MM0523-9G19] to RECK -
Host species
Mouse -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant full length Human RECK protein.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Constituent: PBS -
Concentration information loading... -
Purity
Protein G purified -
Purification notes
The IgG fraction of culture supernatant was purified by protein G affinity chromatography and 0.2 µm filtered. -
Clonality
Monoclonal -
Clone number
MM0523-9G19 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab89915 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/1000. Predicted molecular weight: 106 kDa. |
Target
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Function
Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression. -
Tissue specificity
Expressed in various tissues and untransformed cells. It is undetectable in tumor-derived cell lines and oncogenically transformed cells. -
Sequence similarities
Contains 3 Kazal-like domains. -
Post-translational
modificationsN-glycosylated. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 313488 Human
- Entrez Gene: 8434 Human
- Omim: 605227 Human
- SwissProt: O95980 Human
- SwissProt: Q5W0K6 Human
- Unigene: 388918 Human
- Unigene: 728961 Human
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Alternative names
- hRECK antibody
- Membrane anchored glycoprotein (metastasis and invasion) antibody
- RECK antibody
see all
Images
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![Western blot - Anti-RECK antibody [MM0523-9G19] (ab89915)](https://www.abcam.com/ps/products/89/ab89915/Images/ab89915-256871-anti-reck-antibody-mm0523-9g19-western-blot.jpg)
Western blot - Anti-RECK antibody [MM0523-9G19] (ab89915)Anti-RECK antibody [MM0523-9G19] (ab89915) at 1/500 dilution + Human liver lysate
Predicted band size: 106 kDa
Protocols
Datasheets and documents
References
ab89915 has not yet been referenced specifically in any publications.
