Recombinant Chicken IL-1RA protein (ab169710)

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Description

  • Product name

    Recombinant Chicken IL-1RA protein
    See all IL-1RA proteins and peptides

  • Purity

    > 95 % SDS-PAGE.
    ab169710 was purified by Ion-exchange chromatography.

  • Expression system

    Yeast

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Chicken

    • Sequence

      SVPCRAPALQ TKVFKYRIWD MNQQSLYLRD DQLVAGHLQG ANAALEEKVF WVPNRFFKHE LQPVIMGIRN GTRCLACPAA PQPTLQLQDA DITELPRSGA ASAPFTFFRT YKDGLWRFES AANPGWFLCT SARAHQPLGL SRRPDAAHVL DFYFQLC

    • Predicted molecular weight

      18 kDa

Specifications

Our Abpromise guarantee covers the use of ab169710 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituents: 90% PBS, 10% Trehalose

  • Reconstitution
    Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. Store reconstituted protein in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.

General Info

  • Alternative names

    • DIRA
    • F630041P17Rik
    • ICIL 1RA
    • ICIL-1RA
    • ICIL1RA
    • IL-1ra
    • IL-1ra3
    • IL-1RN
    • IL1 inhibitor
    • IL1F3
    • IL1RA
    • IL1RA_HUMAN
    • IL1RN
    • IL1RN (IL1F3)
    • Interleukin 1 receptor antagonist
    • Interleukin-1 receptor antagonist protein
    • Intracellular IL 1 receptor antagonist type II
    • Intracellular interleukin 1 receptor antagonist (icIL 1ra)
    • IRAP
    • MGC10430
    • MVCD4
    • Type II interleukin 1 receptor antagonist
    see all

  • Function

    Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure.

  • Tissue specificity

    The intracellular form of IL1RN is predominantly expressed in epithelial cells.

  • Involvement in disease

    Microvascular complications of diabetes 4
    Interleukin 1 receptor antagonist deficiency

  • Cellular localization

    Cytoplasm and Secreted.
  • Information by UniProt

References

ab169710 has not yet been referenced specifically in any publications.

Publishing research using ab169710? Please let us know so that we can cite the reference in this datasheet.

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