Recombinant Chicken IL-1RA protein (ab169710)
Key features and details
- Expression system: Yeast
- Purity: > 95% SDS-PAGE
- Suitable for: SDS-PAGE
Description
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Product name
Recombinant Chicken IL-1RA protein
See all IL-1RA proteins and peptides -
Purity
> 95 % SDS-PAGE.
ab169710 was purified by Ion-exchange chromatography. -
Expression system
Yeast -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Chicken -
Sequence
SVPCRAPALQ TKVFKYRIWD MNQQSLYLRD DQLVAGHLQG ANAALEEKVF WVPNRFFKHE LQPVIMGIRN GTRCLACPAA PQPTLQLQDA DITELPRSGA ASAPFTFFRT YKDGLWRFES AANPGWFLCT SARAHQPLGL SRRPDAAHVL DFYFQLC -
Predicted molecular weight
18 kDa
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Specifications
Our Abpromise guarantee covers the use of ab169710 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at -20ºC.
Constituents: 90% PBS, 10% Trehalose
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ReconstitutionReconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. Store reconstituted protein in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
General Info
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Alternative names
- DIRA
- F630041P17Rik
- ICIL 1RA
see all -
Function
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure. -
Tissue specificity
The intracellular form of IL1RN is predominantly expressed in epithelial cells. -
Involvement in disease
Microvascular complications of diabetes 4
Interleukin 1 receptor antagonist deficiency -
Cellular localization
Cytoplasm and Secreted. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab169710 has not yet been referenced specifically in any publications.