Recombinant Chicken IL-21 protein (ab136370)
- Datasheet
- References
- Protocols
Overview
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Product name
Recombinant Chicken IL-21 protein
See all IL-21 proteins and peptides -
Protein length
Full length protein
Description
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Nature
Recombinant -
Source
Yeast -
Amino Acid Sequence
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Species
Chicken -
Sequence
ATSPKAMKYK QLSKTIDHLK DVVKDKDVEL LHTPENPGDG CLLTAVTCFQ NGILKLQPKN SQVNATFAKT VKILRRPFLP VSEGHCESSC ESYERKKPQE FLNSFSKLMQ KLFKNSTAER YGKSTI -
Molecular weight
14 kDa -
Amino acids
20 to 145
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Specifications
Our Abpromise guarantee covers the use of ab136370 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Purity
> 95 % SDS-PAGE.
ab136370 was purified by Ion-exchange chromatography. -
Form
Lyophilised -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.
Constituents: 89% PBS, 10% Trehalose
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ReconstitutionReconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
General Info
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Alternative names
- CVID11
- IL 21
- IL-21
see all -
Function
Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation. -
Tissue specificity
Expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes. -
Sequence similarities
Belongs to the IL-15/IL-21 family. -
Cellular localization
Secreted. - Information by UniProt
Datasheets and documents
References
ab136370 has not yet been referenced specifically in any publications.
