Overview

Description

  • Nature

    Recombinant
  • Source

    Yeast
  • Amino Acid Sequence
    • Accession
    • Species

      Chicken
    • Sequence

      CNHLRPQDAT FSHDSLQLLR DMAPTLPQLC PQHNASCSFN DTILDTSNTR QADKTTHDIL QHLFKILSSP STPAHWNDSQ RQSLLNRIHR YTQHLEQCLD SSDTRSRTRW PRNLHLTIKK HFSCLHTFLQ DNDYSACAWE HVRLQARAWF LHIHNLTGNT RT
    • Molecular weight

      19 kDa
    • Amino acids

      32 to 193

Specifications

Our Abpromise guarantee covers the use of ab136353 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity

    Recombinant chicken IFN-alpha significantly increased IL-6 expression in RP9 cells, a retrovirus-transformed B cell line, as determined by real-time PCR, in a dose-dependent manner with concentrations of 62.5 ng/mL to 1000 ng/mL recombinant chicken IFN-alpha.

  • Applications

    Functional Studies

    SDS-PAGE

  • Purity

    > 95 % SDS-PAGE.
    ab136353 was purified by Ion-exchange chromatography.
  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    Constituents: 89% PBS, 10% Trehalose

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Reconstitute with sterile PBS containing at least 0.1% carrier protein.

General Info

  • Alternative names

    • IFL
    • IFN
    • IFN alpha
    • IFN alpha 1/13
    • IFN alpha 1b
    • IFN alphaD
    • IFN-alpha-1/13
    • IFNA@
    • IFNA1
    • IFNA1_HUMAN
    • IFNA13
    • Interferon alpha 1
    • Interferon alpha-1/13
    • Interferon alpha-D
    • Interferon alpha1
    • Interferon, alpha 13
    • LeIF D
    see all
  • Function

    Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
  • Sequence similarities

    Belongs to the alpha/beta interferon family.
  • Cellular localization

    Secreted.
  • Information by UniProt

References

ab136353 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab136353.
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