Description

  • Product name

    Recombinant Cynomolgus monkey Axl protein (His tag)
    See all Axl proteins and peptides
  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

    < 1.000 Eu/µg
  • Expression system

    HEK 293 cells
  • Accession

  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Cynomolgus monkey
    • Sequence

      IPVIEPSGPELV VKPGETVTLR CVGNGSVEWD GPISPHWTLY SDGPSSVLTT NNATFQNTRT YRCTEPGDPL RGSAAIHLYV KDPARPWNVL AKEVVVFEDQ DALLPCLLTD PVLEAGVSLV RLRGRPLLRH TNYSFSPWHG FIIHRAKFIQ GQDYQCSALM GGRKVMSISI RLKVQKVIPG PPALTLVPEE LVRIRGEAAQ IVCSASNIDV DFDVFLQHNT TKLAIPQRSD FHDNRYQKVL TLSLGQVDFQ HAGNYSCVAS NVQGKHSTSM FFRVVESAYL DLSSEQNLIQ EVTVGEGLNL KVMVEAYPGL QGFNWTYLGP FSDHQPEPKL ANATTKDTYR HTFTLSLPRL KPSEAGRYSF LARNPGGWRA LTFELTLRYP PEVSVIWTSI NGSGTLLCAA SGYPQPNVTW LQCAGHTDRC DEAQVLQVWV DPHPEVLSQE PFQKVTVQSL LTTETLEHNQ TYECRAHNSV GSGSWAFIPI SAGARTHPPD EFLFTP
    • Predicted molecular weight

      57 kDa including tags
    • Amino acids

      99 to 596
    • Tags

      His tag C-Terminus

Specifications

Our Abpromise guarantee covers the use of ab220565 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 95% PBS, 5% Trehalose

    Note: 5-10% trehalose is commonly used for freeze drying, and after reconstitution, the trehalose is mostly about 3-5%.

  • Reconstitution
    It is recommended to reconstitute the lyophilized protein in sterile deionized water to a final concentration of 1mg/ml. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% HSA or BSA) is strongly recommended for further dilution and long term storage.

General Info

  • Alternative names

    • Adhesion related kinase
    • AI323647
    • Ark
    • Axl
    • AXL oncogene
    • AXL receptor tyrosine kinase
    • AXL transforming gene
    • AXL transforming sequence/gene
    • EC 2.7.10.1
    • JTK11
    • Oncogene AXL
    • Tyro7
    • Tyrosine protein kinase receptor UFO
    • Tyrosine-protein kinase receptor UFO
    • UFO
    • UFO_HUMAN
    see all
  • Function

    May function as a signal transducer between specific cell types of mesodermal origin. In case of filovirus infection, seems to function as a cell entry factor.
  • Tissue specificity

    Highly expressed in metastatic colon tumors. Expressed in primary colon tumors. Weakly expressed in normal colon tissue.
  • Sequence similarities

    Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.
    Contains 2 fibronectin type-III domains.
    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 protein kinase domain.
  • Cellular localization

    Membrane.
  • Information by UniProt

Images

  • Immobilized ab220565 at 5 μg/mL (100 μL/well) can bind Biotinylated Human M-CSF, His,Avitag (ab246167) with a linear range of 2-16 ng/mL

  • SDS-PAGE analysis of reduced ab220565 stained overnight with Coomassie Blue.

    The protein migrates as 70-100 kDa under reducing conditions (SDS-PAGE) due to glycosylation.

References

ab220565 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab220565.
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