Bioactive grade

Recombinant cynomolgus monkey CD137 protein (Active) (ab220574)

Description

  • Product name

    Recombinant cynomolgus monkey CD137 protein (Active)
    See all CD137 proteins and peptides
  • Biological activity

    Immobilized ab220574 at 1μg/mL (100 µL/well), can bind Human 4-1BB Ligand, Fc Tag with a linear range of 0.01-0.5 ng/mL.

  • Purity

    > 92 % SDS-PAGE.

  • Endotoxin level

    < 1.000 Eu/µg
  • Expression system

    HEK 293 cells
  • Accession

  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Cynomolgus monkey
    • Sequence

      LQDLCSNCPAGTFCDNNRSQICSPCPPNSFSSAGGQRTCDICRQCKGVFK TRKECSSTSNAECDCISGYHCLGAECSMCEQDCKQGQELTKKGCKDCCFG TFNDQKRGICRPWTNCSLDGKSVLVNGTKERDVVCGPSPADLSPGASSAT PPAPAREPGHSPQ
    • Predicted molecular weight

      19 kDa
    • Amino acids

      24 to 186
    • Tags

      His tag C-Terminus
    • Additional sequence information

      (Accession # XP_005544945.1).

Specifications

Our Abpromise guarantee covers the use of ab220574 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 95% PBS, 5% Trehalose

    Lyophilized from 0.22 µm filtered solution.
    5-10% trehalose is commonly used for freeze drying, and after reconstitution, the trehalose is mostly about 3-5%

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    It is recommended to reconstitute the lyophilized product in sterile deionized water to a final concentration of 1 mg/mL. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% HSA or BSA) is strongly recommended for further dilution and long term storage.

General Info

  • Alternative names

    • 4 1BB
    • 4 1BB ligand receptor
    • 4-1BB ligand receptor
    • 4-1BB Ligand Receptor T Cell
    • 4-1BB, mouse, homolog of
    • Antigen 4-1BB Homolog
    • CD 137
    • CD137
    • CD137 antigen
    • CDw137
    • HLDA VI
    • Homolog of mouse 4 1BB
    • ILA
    • Induced by lymphocyte activation
    • induced by lymphocyte activation (ILA)
    • Interleukin activated receptor homolog of mouse Ly63
    • Ly63, mouse, homolog of
    • MGC2172
    • OTTHUMP00000044294
    • Receptor protein 4 1BB
    • T cell antigen 4 1BB homolog
    • T cell antigen ILA
    • T-cell antigen 4-1BB homolog
    • T-cell antigen ILA
    • TNF receptor superfamily member 9
    • TNFRSF9
    • TNR9_HUMAN
    • Tumor necrosis factor receptor superfamily member 9
    see all
  • Function

    Receptor for TNFSF14/4-1BBL. Possibly active during T cell activation.
  • Tissue specificity

    Expressed on the surface of activated T-cells.
  • Sequence similarities

    Contains 4 TNFR-Cys repeats.
  • Cellular localization

    Membrane.
  • Information by UniProt

Images

  • Immobilized ab220574 at 1μg/mL (100 µL/well), can bind Human 4-1BB Ligand, Fc Tag with a linear range of 0.01-0.5 ng/mL.

  • SDS-PAGE analysis of ab220574 under reducing conditions, stained overnight with Coomassie Blue.  The purity of the protein is greater than 92%.  As a result of glycosylation, the reduced protein migrates as 30-40 kDa.

References

ab220574 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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