Recombinant Cynomolgus monkey MCSF Receptor protein (Fc Chimera) (ab220532)

Description

  • Product name

    Recombinant Cynomolgus monkey MCSF Receptor protein (Fc Chimera)
    See all MCSF Receptor proteins and peptides
  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

    < 1.000 Eu/µg
  • Expression system

    HEK 293 cells
  • Accession

  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Cynomolgus monkey
    • Predicted molecular weight

      82 kDa including tags
    • Amino acids

      99 to 596
    • Additional sequence information

      This protein carries a human IgG1 Fc tag at the C-terminus.

Specifications

Our Abpromise guarantee covers the use of ab220532 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.50
    Constituents: 0.75% Glycine, 5% Trehalose, 0.61% Tris

    Lyophilized from 0.22 µm filtered solution.
    5-10% trehalose is commonly used for freeze drying, and after reconstitution, the trehalose is mostly about 3-5%

  • Reconstitution
    It is recommended to reconstitute the lyophilized product in sterile deionized water to a final concentration of 1 mg/mL. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% HSA or BSA) is strongly recommended for further dilution and long term storage. No activity loss was observed after storage at: In lyophilized state for 1 year (4degC); After reconstitution under sterile conditions for 3 months (-70degC).

General Info

  • Alternative names

    • C FMS
    • CD 115
    • CD115
    • CD115 antigen
    • CFMS
    • Colony stimulating factor 1 receptor
    • Colony stimulating factor I receptor
    • CSF 1 R
    • CSF 1R
    • CSF-1 receptor
    • CSF-1-R
    • CSF1 R
    • CSF1R
    • CSF1R_HUMAN
    • CSFR
    • EC 2.7.10.1
    • FIM 2
    • FIM2
    • FMS
    • FMS proto oncogene
    • FMS protooncogene
    • HDLS
    • M-CSF Receptor
    • M-CSF-R
    • Macrophage colony stimulating factor 1 receptor
    • Macrophage colony stimulating factor I receptor
    • Macrophage colony-stimulating factor 1 receptor
    • McDonough feline sarcoma viral (v fms) oncogene homolog
    • MCSFR
    • Oncogen FMS
    • Proto-oncogene c-Fms
    • V-FMS McDonough feline sarcoma viral oncogen homolog, formerly
    see all
  • Function

    Protein tyrosine-kinase transmembrane receptor for CSF1 and IL34.
  • Tissue specificity

    Expressed in bone marrow and in differentiated blood mononuclear cells.
  • Sequence similarities

    Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 protein kinase domain.
  • Cellular localization

    Membrane.
  • Information by UniProt

Images

  • Immobilized Human M-CSF, His Tag at 5 μg/mL (100 μL/well) can bind ab220532 with a linear range of 1-39 ng/mL 

  • Immobilized Biotinylated Human MCSF, His,Avitag (ab246167) at 2 μg/mL (100 μL/well) on streptavidin precoated (0.2 μg/well) plate, can bind ab220532 with a linear range of 1-39 ng/mL

  • SDS-PAGE - Recombinant Cynomolgus monkey Axl protein (Fc Chimera) (ab220532).

    The gel was stained overnight with Coomassie Blue.

    As a result of glycosylation, the protein migrates as 110-125 kDa under reducing (R) conditions and 200- 240 kDa under non-reducing (NR) conditions.

References

ab220532 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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