Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Suitable for: ELISA, WB
Product nameRecombinant Cytomegalovirus Glycoprotein B
See all Cytomegalovirus Glycoprotein B proteins and peptides
Biological activityImmunoreactive with sera of CMV infected individuals.
Purity> 95 % SDS-PAGE.
Sepharose derived purification.
Expression systemEscherichia coli
Protein lengthProtein fragment
Additional sequence informationThe protein contains the Cytomegalovirus (CMV) gB immunodominant regions.
Our Abpromise guarantee covers the use of ab43040 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 0.395% Tris HCl, 0.0292% EDTA, 50% Glycerol
- CMV glycoprotein B
- Glycoprotein B
RelevanceHuman cytomegalovirus (HCMV) glycoprotein B (gB) is an abundant virion envelope protein that has been shown to be essential for the infectivity of HCMV. HCMV gB is also one of the most immunogenic virus-encoded proteins, and a significant fraction of virus neutralizing antibodies are directed at gB.
Cellular localizationVirus envelope.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab43040 has been referenced in 3 publications.
- Richardson SI et al. IgG3 enhances neutralization potency and Fc effector function of an HIV V2-specific broadly neutralizing antibody. PLoS Pathog 15:e1008064 (2019). PubMed: 31841557
- Pires F et al. A rapid magnetic particle-based enzyme immunoassay for human cytomegalovirus glycoprotein B quantification. J Pharm Biomed Anal 156:372-378 (2018). PubMed: 29758495
- Crawford LB et al. Human Cytomegalovirus Induces Cellular and Humoral Virus-specific Immune Responses in Humanized BLT Mice. Sci Rep 7:937 (2017). ELISA . PubMed: 28428537