Recombinant Dog BAFF protein (ab169715)
- Datasheet
- References
- Protocols
Description
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Product name
Recombinant Dog BAFF protein
See all BAFF proteins and peptides -
Purity
> 95 % SDS-PAGE.
ab169715 was purified by Ion-exchange chromatography. -
Expression system
Yeast -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Dog -
Sequence
AIQGPEETVT QDCLQLIADS DTPTIRKGAY TFVPWLLSFK RGRALEEKEN KILVKEAGYF FIYSQVLYTD NTFAMGHLIQ RKKVHVFGDE LSLVTLFRCI QNMPETLPNN SCYSAGIAKL EEGDELQLAI PREDAKISRD GDGTFFGALK LL -
Predicted molecular weight
17 kDa
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Specifications
Our Abpromise guarantee covers the use of ab169715 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Lyophilised -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at -20ºC.
Constituents: 90% PBS, 10% Trehalose
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ReconstitutionReconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. Store reconstituted protein in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
General Info
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Alternative names
- ApoL related ligand TALL 1
- B cell Activating Factor
- B lymphocyte stimulator
see all -
Function
Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B-and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response. -
Tissue specificity
Abundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bone marrow, T-cells and dendritic cells. A lower expression seen in placenta, heart, lung, fetal liver, thymus, and pancreas. -
Sequence similarities
Belongs to the tumor necrosis factor family. -
Post-translational
modificationsThe soluble form derives from the membrane form by proteolytic processing.
N-glycosylated. -
Cellular localization
Secreted and Cell membrane. - Information by UniProt
Datasheets and documents
References
ab169715 has not yet been referenced specifically in any publications.