Recombinant Dog IL-21 protein (ab101290)
- Datasheet
- References
- Protocols
Description
-
Product name
Recombinant Dog IL-21 protein
See all IL-21 proteins and peptides -
Purity
> 95 % SDS-PAGE.
ab101290 was purified by ion-exchange chromatography -
Expression system
Yeast -
Accession
-
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
-
Species
Dog -
Sequence
HKSSFQEQDL LLIRMRQLID IVDQLKNYVN DLDPESLPAP EDVKRHCERS AFSCFQKVQL KAANTGGNEQ IINVLTKQLK RKLPPTNAGR RQKHRPACPS CDSYEKAPPK EFLERLKSLI QKMIHQHLS -
Predicted molecular weight
15 kDa -
Amino acids
18 to 146
-
Specifications
Our Abpromise guarantee covers the use of ab101290 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
Applications
SDS-PAGE
-
Form
Lyophilised -
Concentration information loading...
Preparation and Storage
-
Stability and Storage
Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.
Constituents: 2.68% PBS, 10% Trehalose
-
ReconstitutionReconstitute with sterile PBS containing at least 0.1% carrier protein (BSA)
General Info
-
Alternative names
- CVID11
- IL 21
- IL-21
see all -
Function
Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation. -
Tissue specificity
Expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes. -
Sequence similarities
Belongs to the IL-15/IL-21 family. -
Cellular localization
Secreted. - Information by UniProt
Datasheets and documents
References
ab101290 has not yet been referenced specifically in any publications.
