• Product name

    Recombinant dog IL-4 protein (Active)
    See all IL-4 proteins and peptides
  • Biological activity

    TF-1 cell proliferation: ED50 ≤ 25 ng/mL (≥ 4.0 x 104 units/mg).

  • Purity

    > 95 % SDS-PAGE.
    Produced using animal-free processes and contains only animal-free raw materials.
  • Endotoxin level

    <=1.000 Eu/µg
  • Expression system

    Escherichia coli
  • Accession

  • Protein length

    Full length protein
  • Animal free

  • Nature

    • Species

    • Sequence

    • Predicted molecular weight

      13 kDa
    • Amino acids

      25 to 132
    • Additional sequence information

      Full length mature chain without signal peptide. Genetically modified E.coli.

Associated products


Our Abpromise guarantee covers the use of ab233676 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies


  • Form

  • Additional notes


    12 months from date of receipt when stored at -20°C to -80°C as supplied. 

    1 month when stored at 4°C after reconstituting as directed.

    3 months when stored at -20°C to -80°C after reconstituting as directed.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at room temperature. Store at -20°C.

    Constituent: 0.1% Trifluoroacetic acid

    Lyophilized from a sterile (0.2 micron) filtered aqueous solution.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Reconstitute with sterile water at 0.1 mg/mL. Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

General Info

  • Alternative names

    • B cell growth factor 1
    • B cell IgG differentiation factor
    • B Cell Stimulatory Factor 1
    • B-cell stimulatory factor 1
    • BCGF 1
    • BCGF1
    • Binetrakin
    • BSF-1
    • BSF1
    • IGG1 induction factor
    • IL 4
    • IL-4
    • IL4
    • IL4_HUMAN
    • Il4e12
    • Interleukin 4
    • Interleukin 4 variant 2
    • Interleukin 4, isoform 1
    • Interleukin-4
    • Lymphocyte stimulatory factor 1
    • MGC79402
    • Pitrakinra
    see all
  • Function

    Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
  • Involvement in disease

    Genetic variations in IL4 may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:601367]; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.
  • Sequence similarities

    Belongs to the IL-4/IL-13 family.
  • Cellular localization

  • Information by UniProt


  • SDS-PAGE - Recombinant dog IL4 protein (Active) (ab233676) at 1 µg.

    Lane 1: Non-reducing conditions.

    Lane 2: Reducing conditions.

    4-20% Tris-Glycine gel stained with Coomassie Blue.

    Expected MW 12.9 kDa.

  • ab233676 induced proliferation of TF-1 cells.


ab233676 has not yet been referenced specifically in any publications.

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