Recombinant EBV Nuclear Antigen/EBNA1 protein (ab138345)

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Description

  • Product name

    Recombinant EBV Nuclear Antigen/EBNA1 protein
    See all EBV Nuclear Antigen/EBNA1 proteins and peptides

  • Purity

    > 95 % SDS-PAGE.

  • Expression system

    Escherichia coli

  • Accession

    P03211

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Sequence

      MSDEGPGTGP GNGLGEKGDT SGPEGSGGSG PQRRGGDNHG RGRGRGRGRG GGRPGAPGGS GSGPRHRDGV RRPQKRPSCI GCKGTHGGTG AGAGAGGAGA GGAGAGGGAG AGGGAGGAGG AGGAGAGGGA GAGGGAGGAG GAGAGGGAGA GGGAGGAGAG GGAGGAGGAG AGGGAGAGGG AGGAGAGGGA GGAGGAGAGG GAGAGGAGGA GGAGAGGAGA GGGAGGAGGA GAGGAGAGGA GAGGAGAGGA GGAGAGGAGG AGAGGAGGAG AGGGAGGAGA GGGAGGAGAG GAGGAGAGGA GGAGAGGAGG AGAGGGAGAG GAGAGGGGRG RGGSGGRGRG GSGGRGRGGS GGRRGRGRER ARGGSRERAR GRGRGRGEKR PRSPSSQSSS SGSPPRRPPP GRRPFFHPVG EADYFEYHQE GGPDGEPDVP PGAIEQGPAD DPGEGPSTGP RGQGDGGRRK KGGWFGKHRG QGGSNPKFEN IAEGLRALLA RSHVERTTDE GTWVAGVFVY GGSKTSLYNL RRGTALAIPQ CRLTPLSRLP FGMAPGPGPQ PGPLRESIVC YFMVFLQTHI FAEVLKDAIK DLVMTKPAPT CNIRVTVCSF DDGVDLPPWF PPMVEGAAAE GDDGDDGDEG GDGDEGEEGQ E

    • Predicted molecular weight

      63 kDa including tags

    • Amino acids

      1 to 641

    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab138345 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

    SDS-PAGE

  • Form

    Liquid

  • Additional notes

     This product was previously labelled as EBV Nuclear Antigen

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 5.8% Sodium chloride, 36% Urea, Phosphate Buffer, 0.1% C13E10

    20mM phosphate buffer.

General Info

  • Alternative names

    • EBNA1
    • EBV nuclear antigen 1
    • Epstein Barr nuclear antigen 1
    • Epstein Barr virus
    • HHV4
    • Human Herpesvirus 4
    see all

  • Relevance

    Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) is the one EBV antigen that is expressed in all EBV associated malignancies. It has long been thought to go undetected by the cell mediated immune system. However, recent studies show that EBNA1 can be presented to both CD4+ and CD8+ T cells, making it a potential new target for immunotherapy of EBV related cancers.

  • Cellular localization

    Nuclear. Free in the nucleoplasm, somewhat associated with the chromatin and hardly, if at all associated with the nuclear matrix.

References

This product has been referenced in:

  • Djureinovic D  et al. Detection of autoantibodies against cancer-testis antigens in non-small cell lung cancer. Lung Cancer 125:157-163 (2018). Read more (PubMed: 30429015) »
See 1 Publication for this product

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