Description

  • Product name

    Recombinant EBV Nuclear Antigen/EBNA1 protein
    See all EBV Nuclear Antigen/EBNA1 proteins and peptides
  • Biological activity

    This protein is immunoreactive with sera of EBV-infected individuals
  • Purity

    > 95 % SDS-PAGE.
    This protein was purified by proprietary chromatographic techniques.
  • Expression system

    Escherichia coli

  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Amino Acid Sequence 1

    • Amino acids

      1 to 90
    • Amino Acid Sequence 2

    • Amino acids

      408 to 498
    • Tags

      His tag C-Terminus

Specifications

Our Abpromise guarantee covers the use of ab68991 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form

    Liquid
  • Additional notes

     This product was previously labelled as EBV Nuclear Antigen

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Constituents: 0.5% Sarkosyl, 0.307% Glutathione, 0.79% Tris HCl, 50% Glycerol, 0.348% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names

    • EBNA1
    • EBV nuclear antigen 1
    • Epstein Barr nuclear antigen 1
    • Epstein Barr virus
    • HHV4
    • Human Herpesvirus 4
    see all
  • Relevance

    Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) is the one EBV antigen that is expressed in all EBV associated malignancies. It has long been thought to go undetected by the cell mediated immune system. However, recent studies show that EBNA1 can be presented to both CD4+ and CD8+ T cells, making it a potential new target for immunotherapy of EBV related cancers.
  • Cellular localization

    Nuclear. Free in the nucleoplasm, somewhat associated with the chromatin and hardly, if at all associated with the nuclear matrix.

References

ab68991 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Answer


The protein is a E.Coli derived recombinant mosaic protein which contains the HHV-4 EBNA regions, 1-90, 408-498 amino acids, the Mw is 46kDa (including 26kDa GST tag).

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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