Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Active: Yes
- Suitable for: ELISA, SDS-PAGE
Product nameRecombinant Hepatitis B Virus Core Antigen protein
See all Hepatitis B Virus Core Antigen proteins and peptides
Biological activityab119441 is immunoreactive with sera from HBV-infected individuals.
Purity> 95 % SDS-PAGE.
Expression systemEscherichia coli
Protein lengthFull length protein
Predicted molecular weight18 kDa
Our Abpromise guarantee covers the use of ab119441 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped on Dry Ice. Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
Constituents: 49% PBS, 50% Glycerol
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- Capsid protein
RelevanceHepatitis B Virus Core Antigen (HBcAg) is part of the infectious virion containing an inner "core particle" enclosing the viral genome. The icosahedral core particle contains 180 or 240 copies of the core protein. HBcAg is one of the three major clinical antigens of hepatitis B virus but disappears early in the course of infection. The hepatitis B virus core antigen (HBcAg) is a highly immunogenic subviral particle and functions as both a T-cell-dependent and a T-cell-independent antigen. Therefore, HBcAg may be a promising candidate target for therapeutic vaccine control of chronic HBV infection.
Cellular localizationCapsid protein: Virion. Host cytoplasm, hepatocyte nucleus.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab119441 has been referenced in 1 publication.
- Li F et al. HBV infection suppresses the expression of inflammatory macrophage miR-210. Mol Med Rep 19:1833-1839 (2019). PubMed: 30592291