Recombinant Hepatitis B Virus Core Antigen protein (ab49013)

Submit an Abreview Q&A (3)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Amino acids
      1 to 183

Specifications

Our Abpromise guarantee covers the use of ab49013 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Reacts strongly with human HBV positive serum.
  • Applications

    SDS-PAGE

    ELISA

    Western blot

  • Purity
    > 95 % SDS-PAGE.

  • Form
    Liquid
  • Additional notes
    Reacts strongly with human HBV positive serum.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.

    pH: 7.20
    Constituents: 0.02% PBS, 50% Glycerol, 0.435% Sodium chloride

General Info

  • Alternative names
    • C
    • Capsid protein
    • core
    • Core and e antigen
    • Core antigen
    • Core protein
    • HBc
    • HBcAg
    • HBVgp4
    • Hepatitis B core antigen
    • Hepatitis B Virus core antigen
    • p21.5
    • precore/core protein
    see all
  • Relevance
    Hepatitis B Virus Core Antigen (HBcAg) is part of the infectious virion containing an inner "core particle" enclosing the viral genome. The icosahedral core particle contains 180 or 240 copies of the core protein. HBcAg is one of the three major clinical antigens of hepatitis B virus but disappears early in the course of infection. The hepatitis B virus core antigen (HBcAg) is a highly immunogenic subviral particle and functions as both a T-cell-dependent and a T-cell-independent antigen. Therefore, HBcAg may be a promising candidate target for therapeutic vaccine control of chronic HBV infection.
  • Cellular localization
    Capsid protein: Virion. Host cytoplasm, hepatocyte nucleus.

References

ab49013 has not yet been referenced specifically in any publications.

Publishing research using ab49013? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

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3 reviews or Q&A

10
Votes: Highest First

I am looking for HBV core antigen of different genotype. I saw you have several product listed on your website, but they do not have genotype information. Could you please let me know the genotype of each of these? Or a sequence would work too.

All three of the core antigen proteins you asked about are from the HBV320 strain, genotype D. The article at this URL, https://www.ncbi.nlm.nih.gov/pubmed/?term=8336122, identifies the genotype of HBV320 and many other strains in Figures 1 and 2.

Please provide C of A ‘s for the following



ab39716 lot *
ab8637 lot G*

ab49013 lot*

ab58713 lot G*


Thank you for contacting Abcam.
Please find attached the requested Certificates of Analysis.
If there is anything else I can help you with, please let me know.

pouvez-vous me dire si la protéine ab49013 est tagguée



Non, la protéine "Hepatitis B Virus Core Antigen" référence ab49013n'est pas taguée.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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