The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
< 1.000 Eu/µg
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40 Constituent: 99% PBS Note: Normally Mannitol or Trehalose are added as protectants before lyophilization
It is recommended to reconstitute the lyophilized protein in 10µl sterile deionized water to a final concentration of 1mg/ml. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% HSA or BSA) is strongly recommended for further dilution and long term storage.
Human Immunodeficiency Virus 1
HIV1 is equipped with the envelope gp160 glycoprotein for interaction with Langerhans cells (LCs) and dendritic cells (DCs), the members of the innate immune system, which confront the virus at the portal of virus entry in the human body. These cells are equipped with receptors by which they bind and endocytose the virus. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4, which inactivates the host adaptive immune response.
SDS-PAGE - HIV-1 gp120 (Du172.17 protein (His tag) (ab167715)
SDS-PAGE of reduced ab167715 stained overnight with Coomassie Blue.
This product has been referenced in:
Dodagatta-Marri E et al. Protein-Protein Interaction between Surfactant Protein D and DC-SIGNviaC-Type Lectin Domain Can Suppress HIV-1 Transfer. Front Immunol8:834 (2017).
Read more (PubMed: 28824609) »