Description

Specifications

Our Abpromise guarantee covers the use of ab49054 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid
  • Additional notes

    This protein can be used to detect all HIV-1 and HIV-type O infected individuals responding to envelope proteins.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.

    Constituents: 0.106% Sodium carbonate, 0.1092% Beta mercaptoethanol, 0.05% Tween, 0.292% EDTA

General Info

  • Alternative names

    • Glycoprotein 120
    • Glycoprotein 41
    • HIV1 gp120
    • HIV1 gp41
    • SU
    • TM
    see all
  • Relevance

    gp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.

References

ab49054 has not yet been referenced specifically in any publications.

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