Recombinant HIV1 gp120 protein (ab217643)
- Datasheet
- References
- Protocols
Description
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Product name
Recombinant HIV1 gp120 protein
See all HIV1 gp120 proteins and peptides -
Purity
> 95 % SDS-PAGE. -
Expression system
HEK 293 cells -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Sequence
VTVYYGVPVWRDADTTLFCASDAKAHETEVHNVWATHACVPTDPNPQEIH LENVTENFNMWKNNMVEQMQEDVISLWDQSLKPCVKLTPLCVTLHCTNAN LTNVNNITNVPNIIGNITDEVRNCSFNMTTELRDKKQKVHALFYKLDIVQ IEDNKKSSSEYRLINCNTSVIKQACPKISFDPIPIHYCTPAGYAILKCND KNFNGTGPCKNVSSVQCTHGIKPVVSTQLLLNGSLAEEEIIIRSEDLTNN AKTIIVHLNKSVEINCTRPSNNTRTSIRIGPGQAFYRTGDIIGDIRKAYC EINGTKWNEALKQVTEKLKEHFNNKTIIFQPPSGGDLEITMHHFNCRGEF FYCNTTRLFNNTCIGNKTMGGCNGTIILPCKIKQIINMWQGAGQAMYAPP ISGRINCVSNITGILLTRDGGAINTTNETFRPGGGNIKDNWRSELYKYKV VQIEPLGIAPTRAKRRV -
Predicted molecular weight
52 kDa -
Amino acids
35 to 501 -
Tags
His tag C-Terminus -
Additional sequence information
6x His-tagged HIV-1/Subtype CRF01_AE.
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Specifications
Our Abpromise guarantee covers the use of ab217643 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Constituents: 74% PBS, 0.1% BSA, 25% Glycerol
General Info
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Alternative names
- Glycoprotein 120
- gp120
- SU
- Surface protein
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Relevance
HIV1 is equipped with the envelope gp160 glycoprotein for interaction with Langerhans cells (LCs) and dendritic cells (DCs), the members of the innate immune system, which confront the virus at the portal of virus entry in the human body. These cells are equipped with receptors by which they bind and endocytose the virus. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4, which inactivates the host adaptive immune response. -
Cellular localization
Envelope surface glycoprotein.
Images
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SDS-PAGE - Recombinant HIV1 gp120 protein (ab217643)ab217643 on SDS-PAGE
Datasheets and documents
References
ab217643 has not yet been referenced specifically in any publications.
