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  1. Link

    recombinant-hiv1-gp120-protein-ab217643.pdf

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Microbiology Organism Virus RNA Virus ssRNA positive strand virus HIV
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Recombinant HIV1 gp120 protein (ab217643)

  • Datasheet
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SDS-PAGE - Recombinant HIV1 gp120 protein (ab217643)

    Key features and details

    • Expression system: HEK 293 cells
    • Purity: > 95% SDS-PAGE
    • Tags: His tag C-Terminus
    • Suitable for: SDS-PAGE

    Description

    • Product name

      Recombinant HIV1 gp120 protein
      See all HIV1 gp120 proteins and peptides
    • Purity

      > 95 % SDS-PAGE.

    • Expression system

      HEK 293 cells
    • Accession

      AAG28611
    • Protein length

      Protein fragment
    • Animal free

      No
    • Nature

      Recombinant
      • Sequence

        VTVYYGVPVWRDADTTLFCASDAKAHETEVHNVWATHACVPTDPNPQEIH LENVTENFNMWKNNMVEQMQEDVISLWDQSLKPCVKLTPLCVTLHCTNAN LTNVNNITNVPNIIGNITDEVRNCSFNMTTELRDKKQKVHALFYKLDIVQ IEDNKKSSSEYRLINCNTSVIKQACPKISFDPIPIHYCTPAGYAILKCND KNFNGTGPCKNVSSVQCTHGIKPVVSTQLLLNGSLAEEEIIIRSEDLTNN AKTIIVHLNKSVEINCTRPSNNTRTSIRIGPGQAFYRTGDIIGDIRKAYC EINGTKWNEALKQVTEKLKEHFNNKTIIFQPPSGGDLEITMHHFNCRGEF FYCNTTRLFNNTCIGNKTMGGCNGTIILPCKIKQIINMWQGAGQAMYAPP ISGRINCVSNITGILLTRDGGAINTTNETFRPGGGNIKDNWRSELYKYKV VQIEPLGIAPTRAKRRV
      • Predicted molecular weight

        52 kDa
      • Amino acids

        35 to 501
      • Tags

        His tag C-Terminus
      • Additional sequence information

        6x His-tagged HIV-1/Subtype CRF01_AE.

    Specifications

    Our Abpromise guarantee covers the use of ab217643 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

      Constituents: 74% PBS, 0.1% BSA, 25% Glycerol

    General Info

    • Alternative names

      • Glycoprotein 120
      • gp120
      • SU
      • Surface protein
    • Relevance

      HIV1 is equipped with the envelope gp160 glycoprotein for interaction with Langerhans cells (LCs) and dendritic cells (DCs), the members of the innate immune system, which confront the virus at the portal of virus entry in the human body. These cells are equipped with receptors by which they bind and endocytose the virus. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4, which inactivates the host adaptive immune response.
    • Cellular localization

      Envelope surface glycoprotein.

    Images

    • SDS-PAGE - Recombinant HIV1 gp120 protein (ab217643)
      SDS-PAGE - Recombinant HIV1 gp120 protein (ab217643)

      ab217643 on SDS-PAGE

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab217643? Please let us know so that we can cite the reference in this datasheet.

    ab217643 has not yet been referenced specifically in any publications.

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