Product nameRecombinant HIV1 + HIV2 envelope antigen protein
See all HIV1 + HIV2 envelope antigen proteins and peptides
Protein lengthProtein fragment
Our Abpromise guarantee covers the use of ab48966 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activityDetects all HIV1,2 infected individuals responding to HIV1,2 envelope proteins.
Additional notesDetects all HIV1,2 infected individuals responding to HIV1,2 envelope proteins.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.01% Sodium azide
Constituents: 9% Urea, 0.395% Tris HCl, 0.0292% EDTA, 50% Glycerol
- Envelope glycoprotein gp160
- Glycoprotein 120
- Glycoprotein 41
RelevanceInhibitors targeting HIV1 viral envelope proteins are used as antiretroviral drugs. The surface protein gp120 attaches the virus to the host lymphoid cell by binding to the primary receptor CD4. This interaction induces a structural rearrangement creating a high affinity binding site for a chemokine coreceptor like CXCR4 and/or CCR5. The transmembrane protein gp41 acts as a class I viral fusion protein.
ab48966 has not yet been referenced specifically in any publications.