Key features and details
- Expression system: Escherichia coli
- Suitable for: ELISA, WB
Product nameRecombinant HIV1 p17 + p24 + gp120 + gp41 protein
Expression systemEscherichia coli
Protein lengthProtein fragment
- Anti-HIV1 gp41 antibody [1D4] (ab18633)
- Anti-HIV1 gp41 antibody (ab20890)
- Anti-HIV1 p24 antibody (FITC) (ab30956)
- Anti-HIV1 p24 antibody [38/8.7.47] (ab9044)
- Anti-HIV1 p17 antibody [32/5.8.42] (ab9064)
- Anti-HIV1 gp41 antibody [10E9] (ab9065)
- Anti-HIV1 p17 antibody [2D11] (ab9067)
- Anti-HIV1 p17 antibody [32/1.24.89] (ab9068)
- Anti-HIV1 p24 antibody [39/5.4A] (ab9071)
Our Abpromise guarantee covers the use of ab49079 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.01% Sodium azide
Constituents: 9% Urea, 0.395% Tris HCl, 0.0292% EDTA, 50% Glycerol (glycerin, glycerine)
- Capsid protein p24
- Glycoprotein 120
RelevanceHIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation, and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors function during viral assembly to selectively bind and package two plus strands of genomic RNA. HIV1 p17 is the matrix protein of the Gag polyprotein. Capsid protein p24 probably forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex. gp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab49079 has not yet been referenced specifically in any publications.