Recombinant HPV16 L1 protein (ab119880)
Key features and details
- Expression system: Saccharomyces cerevisiae
- Purity: > 90% SDS-PAGE
- Suitable for: WB, SDS-PAGE, Electron Microscopy
Description
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Product name
Recombinant HPV16 L1 protein -
Purity
> 90 % SDS-PAGE.
ab119880 is purified by ultracentifugation. -
Expression system
Saccharomyces cerevisiae -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Sequence
MSLWLPSEATVYLPPVPVSKVVSTDEYVARTNIYYHAGTSRLLAVGHPYF PIKKPNNNKILVPKVSGLQYRVFRIHLPDPNKFGFPDTSFYNPDTQRLVW ACVGVEVGRGQPLGVGISGHPLLNKLDDTENASAYAANAGVDNRECISMD YKQTQLCLIGCKPPIGEHWGKGSPCTNVAVNPGDCPPLELINTVIQDGDM VDTGFGAMDFTTLQANKSEVPLDICTSICKYPDYIKMVSEPYGDSLFFYL RREQMFVRHLFNRAGAVGENVPDDLYIKGSGSTANLASSNYFPTPSGSMV TSDAQIFNKPYWLQRAQGHNNGICWGNQLFVTVVDTTRSTNMSLCAAIST SETTYKNTNFKEYLRHGEEYDLQFIFQLCKITLTADVMTYIHSMNSTILE DWNFGLQPPPGGTLEDTYRFVTSQAIACQKHTPPAPKEDPLKKYTFWEVN LKEKFSADLDQFPLGRKFLLQAGLKAKPKFTLGKRKATPTTSSTSTTAKR KKRKL -
Predicted molecular weight
56 kDa -
Amino acids
1 to 505
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Specifications
Our Abpromise guarantee covers the use of ab119880 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
SDS-PAGE
Electron Microscopy
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.
Constituent: 99% PBS
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ReconstitutionReconstitute in 50 ul of water. Then dilute with PBS to the required concentration.
General Info
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Alternative names
- HPV-16
- HPV-16 capsid
- HPV16 capsid protein
see all -
Relevance
L1 is a major capsid protein of type 16 human papilloma virus. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. -
Cellular localization
Virion. Host Nucleus.
Images
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SDS-PAGE analysis of ab119880.
Lane 1. ab119880
Lane 2. MWt marker -
Western blot analysis of ab119880.
Lane 1. MWt marker
Lane 2. ab119808 -
ab119880 viewed by electron microscopy.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab119880 has been referenced in 2 publications.
- Read BJ et al. Mannose-binding lectin and complement mediate follicular localization and enhanced immunogenicity of diverse protein nanoparticle immunogens. Cell Rep 38:110217 (2022). PubMed: 35021101
- Eto Y et al. Expression of Chimeric HPV-HIV Protein L1P18 in Pichia pastoris; Purification and Characterization of the Virus-like Particles. Pharmaceutics 13:N/A (2021). PubMed: 34834382