Recombinant HSV1 gD protein (ab43045)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Tags: GST tag N-Terminus
- Suitable for: ELISA, WB
Description
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Product name
Recombinant HSV1 gD protein
See all HSV1 gD proteins and peptides -
Biological activity
Immunoreactive with sera of HSV infected individuals, excellent antigen for detection of HSV with minimal specificity problems. -
Purity
> 95 % SDS-PAGE.
Sepharose derived purification. -
Expression system
Escherichia coli -
Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Predicted molecular weight
40 kDa -
Amino acids
266 to 394 -
Tags
GST tag N-Terminus -
Additional sequence information
The protein contains the HSV-1 gD immunodominant regions.
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Specifications
Our Abpromise guarantee covers the use of ab43045 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
ELISA
Western blot
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Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 0.395% Tris HCl, 0.0292% EDTA, 50% Glycerol
General Info
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Alternative names
- GD
- Glycoprotein D
- Herpes simplex virus type 1 glycoprotein D
- HSV1 glycoprotein D
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Relevance
Herpes simplex type 1 (HSV-1) belongs to a family that includes HSV-2, Epstein-Barr virus (EBV) and Varicella zoster (chicken pox) virus amongst others. HSV-1 and HSV-2 are extremely difficult to distinguish from each other. Members of this family have a characteristic virion structure. The double stranded DNA genome is contained within an icosahedral capsid embedded in a proteinaceous layer (tegument) and surrounded by a lipid envelope, derived from the nuclear membrane of the last host, which is decorated with virus-specific glycoproteins spikes. These viruses are capable of entering a latent phase where the host shows no visible sign of infection and levels of infectious agent become very low. During the latent phase the viral DNA is integrated into the genome of the host cell. Glycoprotein D (gD) has been implicated in binding to cellular receptors that facilitate virus penetration into cells. Herpes simplex virus type 1 (HSV-1) glycoprotein D (gD) is an essential component of the entry apparatus that is responsible for viral penetration and subsequent cell-cell spread.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab43045 has not yet been referenced specifically in any publications.