Product nameRecombinant HSV1 gD protein
See all HSV1 gD proteins and peptides
Protein lengthProtein fragment
Amino Acid Sequence
Additional sequence informationThe protein contains the HSV-1 gD immunodominant regions.
Our Abpromise guarantee covers the use of ab43045 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activityImmunoreactive with sera of HSV infected individuals, excellent antigen for detection of HSV with minimal specificity problems.
Purity> 95 % SDS-PAGE.
Sepharose derived purification.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 0.395% Tris HCl, 0.0292% EDTA, 50% Glycerol
- Glycoprotein D
- Herpes simplex virus type 1 glycoprotein D
- HSV1 glycoprotein D
RelevanceHerpes simplex type 1 (HSV-1) belongs to a family that includes HSV-2, Epstein-Barr virus (EBV) and Varicella zoster (chicken pox) virus amongst others. HSV-1 and HSV-2 are extremely difficult to distinguish from each other. Members of this family have a characteristic virion structure. The double stranded DNA genome is contained within an icosahedral capsid embedded in a proteinaceous layer (tegument) and surrounded by a lipid envelope, derived from the nuclear membrane of the last host, which is decorated with virus-specific glycoproteins spikes. These viruses are capable of entering a latent phase where the host shows no visible sign of infection and levels of infectious agent become very low. During the latent phase the viral DNA is integrated into the genome of the host cell. Glycoprotein D (gD) has been implicated in binding to cellular receptors that facilitate virus penetration into cells. Herpes simplex virus type 1 (HSV-1) glycoprotein D (gD) is an essential component of the entry apparatus that is responsible for viral penetration and subsequent cell-cell spread.
ab43045 has not yet been referenced specifically in any publications.