Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Amino acids
      266 to 394
    • Additional sequence information
      The protein contains the HSV-2 gD immunodominant regions.

Specifications

Our Abpromise guarantee covers the use of ab43046 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity

    Immunoreactive with sera from HSV2-infected individuals with minimum specificity problems.

  • Applications

    ELISA

    Western blot

  • Purity
    > 95 % SDS-PAGE.
    Sepharose derived purification.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Constituents: 0.395% Tris HCl, 0.0292% EDTA, 50% Glycerol

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • Glycoprotein D precursor
    • Herpes Simplex Virus Type 2 Glycoprotein D
    • Human Herpesvirus 2
    • US6
    • Virion glycoprotein D
    see all
  • Relevance
    There are eight members of the herpes virus family that are known to cause human disease, including not only the herpes simplex viruses (HSV1 and HSV2). HSV1 and HSV2 are family Herpesviridae, subfamily Alpha herpes virinae, genus Simplexvirus. Glycoprotein D(gD) binds specifically to the herpesvirus entry mediator receptor (HVEM), thus providing a strong, fixed attachment to the host cell. These interactions bring the membrane surfaces into mutual proximity and allow for other surface glycoproteins to interact.

References

ab43046 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

1-2 of 2 Abreviews or Q&A

Question
Answer

Thank you very much for your call today and for your patience.

I've heard back from the lab, and the protein has a MW of 45.50 kDa, including a 26 kDa GST fusion. We did not determine its isoelectric point unfortunately.

I am sorry that we don't have all the information you're looking for, but if you have further questions or need anything else, please let me know and I'll be happy to help.

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Answer

I am sorry to hear that you have been experiencing problems using this product in the application that you wish.

In order to assess the quality of our products I would ask that you complete a brief questionnaire relating to the application used. Often it is possible to make suggestions that may help resolve problems experienced using a particular product.

As our Abpromise indicates, in the event that a product is not functioning in the applications/species cited on the product data sheet (and the problem has been reported within 6 months of purchase) we will happily offer a credit note/refund to the value of the product purchased.

All our customer feedback, including complaints are monitored weekly by our in house technical support team. If a product is at fault the technical support team will consider removing the product from our catalogue in order to avoid future customer inconvenience.

Could you provide some further details of the protocol used and complete the following form (attached as a word document). It would be much appreciated if you could attach an image to the response.

Thank you for your understanding and co-operation in this matter. I look forward to hearing from you soon and resolving this issue as soon as possible.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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