Recombinant Human ACADM/MCAD protein (ab173059)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Endotoxin level: < 1.000 Eu/µg
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE, HPLC
Description
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Product name
Recombinant Human ACADM/MCAD protein
See all ACADM/MCAD proteins and peptides -
Purity
> 95 % SDS-PAGE.
The purity of ab173059 is greater than 95%, as determined by SEC-HPLC and reducing SDS-PAGE. -
Endotoxin level
< 1.000 Eu/µg -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
KANRQREPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPV PLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEG NSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTK AEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVE ADTPGIQIGRKELNMGQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMG AFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQAISFMLAE MAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAFAGDIANQLATDAVQI LGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDKYKN -
Predicted molecular weight
46 kDa including tags -
Amino acids
26 to 421 -
Tags
His tag N-Terminus -
Additional sequence information
Sequence for the tag: MGSSHHHHHHSSGLVPRGSHM
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab173059 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
HPLC
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Form
Liquid -
Additional notes
Previously labelled as ACADM.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on Dry Ice. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 8.50
Constituents: 0.24% Tris, 0.58% Sodium chloride, 20% Glycerol (glycerin, glycerine)
ab173059 is supplied as a 0.2 µM filtered solution.
General Info
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Alternative names
- ACAD 1
- ACAD1
- Acadm
see all -
Function
This enzyme is specific for acyl chain lengths of 4 to 16. -
Pathway
Lipid metabolism; mitochondrial fatty acid beta-oxidation. -
Involvement in disease
Defects in ACADM are the cause of acyl-CoA dehydrogenase medium-chain deficiency (ACADMD) [MIM:201450]. It is an autosomal recessive disease which causes fasting hypoglycemia, hepatic dysfunction, and encephalopathy, often resulting in death in infancy. -
Sequence similarities
Belongs to the acyl-CoA dehydrogenase family. -
Cellular localization
Mitochondrion matrix. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab173059 has not yet been referenced specifically in any publications.