The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
The activity is determined by the ability to induce cytoxicity of MPC-11 cells and is typically less than 2 ng/mL.
< 1.000 Eu/µg
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot. Store at -20°C long term. For long term storage it is recommended to add a carrier protein on reconstitution (0.1% HSA or BSA).
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Activin beta A chain
Activin beta-A chain
Erythroid differentiation factor
Erythroid differentiation protein
Inhibin beta A chain
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
Functional Studies - Active human Activin A full length protein (ab179491)
Induction of cytotoxicity in MPC-11 cells using ab179491. Assays were carried out in duplicate.
This product has been referenced in:
He XT et al. The effects of conditioned media generated by polarized macrophages on the cellular behaviours of bone marrow mesenchymal stem cells. J Cell Mol Med22:1302-1315 (2018).
Read more (PubMed: 29106032) »