Recombinant Human Acyl-coenzyme A Thioesterase 8 protein (ab156739)

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Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
      O14734
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MGSMSSPQAP EDGQGCGDRG DPPGDLRSVL VTTVLNLEPL DEDLFRGRHY WVPAKRLFGG QIVGQALVAA AKSVSEDVHV HSLHCYFVRA GDPKLPVLYQ VERTRTGSSF SVRSVKAVQH GKPIFICQAS FQQAQPSPMQ HQFSMPTVPP PEELLDCETL IDQYLRDPNL QKRYPLALNR IAAQEVPIEI KPVNPSPLSQ LQRMEPKQMF WVRARGYIGE GDMKMHCCVA AYISDYAFLG TALLPHQWQH KVHFMVSLDH SMWFHAPFRA DHWMLYECES PWAGGSRGLV HGRLWRQDGV LAVTCAQEGV IRVKPQVSES KL
    • Molecular weight
      38 kDa including tags
    • Amino acids
      1 to 319
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab156739 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity
    >95% by SDS-PAGE .
    ab156739 was purified by using conventional chromatography techniques.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.03% DTT, 0.32% Tris HCl, 40% Glycerol, 1.17% Sodium chloride

General Info

  • Alternative names
    • ACTEIII
    • Acot8
    • ACOT8_HUMAN
    • Acyl CoA thioesterase 8
    • Acyl-CoA thioesterase 8
    • Acyl-coenzyme A thioesterase 8
    • Choloyl coenzyme A thioesterase
    • Choloyl-coenzyme A thioesterase
    • hACTE III
    • hACTE-III
    • hACTEIII
    • HIV Nef associated acyl CoA thioesterase
    • HIV-Nef-associated acyl-CoA thioesterase
    • HNAACTE
    • hTE
    • Long chain fatty acyl CoA hydrolase
    • Palmitoyl CoA hydrolase
    • Peroxisomal acyl CoA thioesterase 1
    • Peroxisomal acyl coenzyme A thioester hydrolase 1
    • Peroxisomal acyl-coenzyme A thioester hydrolase 1
    • Peroxisomal long chain acyl CoA thioesterase 1
    • Peroxisomal long-chain acyl-CoA thioesterase 1
    • PTE 1
    • PTE 2
    • PTE-1
    • PTE-2
    • PTE1
    • PTE2
    • Thioesterase II
    see all
  • Function
    Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May mediate Nef-induced down-regulation of CD4. Major thioesterase in peroxisomes. Competes with BAAT (Bile acid CoA: amino acid N-acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs (By similarity). May be involved in the metabolic regulation of peroxisome proliferation.
  • Tissue specificity
    Detected in a T-cell line (at protein level). Ubiquitous.
  • Sequence similarities
    Belongs to the C/M/P thioester hydrolase family.
  • Cellular localization
    Peroxisome.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human Acyl-coenzyme A Thioesterase 8 protein (ab156739)
    SDS-PAGE - Recombinant Human Acyl-coenzyme A Thioesterase 8 protein (ab156739)
    15% SDS-PAGE analysis of ab156739 (3µg)

References

ab156739 has not yet been referenced specifically in any publications.

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