Overview

  • Product name

    Recombinant Human ADAM11 protein
  • Protein length

    Protein fragment

Description

  • Nature

    Recombinant
  • Source

    Wheat germ
  • Amino Acid Sequence
    • Species

      Human
    • Sequence

      GHPTVHSETKYVELIVINDHQLFEQMRQSVVLTSNFAKSVVNLADVIYKE QLNTRIVLVAMETWADGDKIQVQDDLLETLARLMVYRREGLPEPSDATHL FSGR
    • Amino acids

      230 to 333
    • Tags

      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab158869 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • A disintegrin and metalloproteinase domain 11
    • ADA11_HUMAN
    • ADAM 11
    • Adam11
    • and cysteine-rich protein
    • Disintegrin and metalloproteinase domain-containing protein 11
    • disintegrin-like
    • MDC
    • Metalloproteinase like, disintegrin like, and cysteine rich protein
    • Metalloproteinase-like
    see all
  • Function

    Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein.
  • Tissue specificity

    Expressed predominantly in brain. Slightly detected or not at all in other tissues.
  • Sequence similarities

    Contains 1 disintegrin domain.
    Contains 1 EGF-like domain.
    Contains 1 peptidase M12B domain.
  • Domain

    A conserved motif [AVN[ED]CD] within the disintegrin-like domain could be involved in the binding to the integrin receptor.
  • Post-translational
    modifications

    The precursor is cleaved by a furin endopeptidase.
  • Cellular localization

    Membrane.
  • Information by UniProt

Images

  • ab158869 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab158869 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab158869.
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