Overview

  • Product name
    Recombinant Human ADAM7 protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MLPGCIFLMILLIPQVKEKFILGVEGQQLVRPKKLPLIQKRDTGHTHDDD ILKTYEEELLYEIKLNRKTLVLHLLRSREFLGSNYSETFYSMKGEAFTRH PQIMDHCFYQGSIVHEYDSAASISTCNGLRGFFRINDQRYLIEPVKYSDE GEHLVFKYNLRVPYGANYSCTELNFTRKTVPGDNESEEDSKIKGIHDEKY VELFIVADDTVYRRNGHPHNKLRNRIWGMVNFVNMIYKTLNIHVTLVGIE IWTHEDKIELYSNIETTLLRFSFWQEKILKTRKDFDHVVLLSGKWLYSHV QGISYPGGMCLPYYSTSIIKDLLPDTNIIANRMAHQLGHNLGMQHDEFPC TCPSGKCVMDSDGSIPALKFSKCSQNQYHQYLKDYKPTCMLNIPFPYNFH DFQFCGNKKLDEGEECDCGPAQECTNPCCDAHTCVLKPGFTCAEGECCES CQIKKAGSICRPAKDECDFPEMCTGHSPACPKDQFRVNGFPCKNSEGYCF MGKCPTREDQCSELFDDEAIESHDICYKMNTKGNKFGYCKNKENRFLPCE EKDVRCGKIYCTGGELSSLLGEDKTYHLKDPQKNATVKCKTIFLYHDSTD IGLVASGTKCGEGMVCNNGECLNMEKVYISTNCPSQCNENPVDGHGLQCH CEEGQAPVACEETLHVTNITILVVVLVLVIVGIGVLILLVRYRKCIKLKQ VQSPPTETLGVENKGYFGDEQQIRTEPILPEIHFLNKPASKDSRGIADPN QSAK
    • Amino acids
      1 to 754
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab160174 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • A disintegrin and metalloproteinase domain 7
    • ADAM 7
    • ADAM metallopeptidase domain 7
    • Adam7
    • ADAM7_HUMAN
    • Disintegrin and metalloproteinase domain-containing protein 7
    • EAPI
    • epididymal apical protein I
    • GP-83
    • Sperm maturation related glycoprotein GP83
    • Sperm maturation-related glycoprotein GP-83
    see all
  • Function
    May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein.
  • Tissue specificity
    Not detected in healthy melanocytes. Expressed in melanoma cells.
  • Involvement in disease
    Note=Has been found to be frequently mutated in melanoma. ADAM7 mutations may play a role in melanoma progression and metastasis.
  • Sequence similarities
    Contains 1 disintegrin domain.
    Contains 1 peptidase M12B domain.
  • Cellular localization
    Membrane.
  • Information by UniProt

Images

  • ab160174 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab160174 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab160174.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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