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Recombinant Human AFF2 protein
Amino Acid Sequence
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.3% Glutathione, 0.79% Tris HCl
- AF4/FMR2 family member 2
- AF4/FMR2 family, member 2
RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure.
Brain (most abundant in hippocampus and amygdala), placenta and lung.
Involvement in disease
Mental retardation, X-linked, associated with fragile site FRAXE
Belongs to the AF4 family.
Nucleus speckle. When splicing is inhibited, accumulates in enlarged speckles.
Information by UniProt
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"