Description

  • Product name

    Recombinant Human AGAP1 protein
  • Expression system

    Wheat germ
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHV IAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEE SPEGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEGEI SFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSN DLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCKSLPNSP SHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPT ANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQ GLPFFVLALTASTYLRPAGARARQSSPWPGRAEGWSDQPALC
    • Predicted molecular weight

      70 kDa
    • Amino acids

      1 to 392

Specifications

Our Abpromise guarantee covers the use of ab131978 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

    SDS-PAGE

  • Form

    Liquid
  • Additional notes

    Protein concentration is above or equal to 0.05 µg/µl.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names

    • AGAP 1
    • AGAP-1
    • Agap1
    • AGAP1_HUMAN
    • Arf GAP with GTP binding proteinlike ANK repeat and PH domains 1
    • Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1
    • ArfGAP with GTPase domain ankyrin repeat and PH domain 1
    • Centaurin gamma 2
    • Centaurin-gamma-2
    • CENTG2
    • Cnt-g2
    • GGAP 1
    • GGAP1
    • GTP binding and GTPase activating protein 1
    • GTP-binding and GTPase-activating protein 1
    • KIAA1099
    • MGC71657
    see all
  • Function

    GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system.
  • Tissue specificity

    Widely expressed.
  • Sequence similarities

    Belongs to the centaurin gamma-like family.
    Contains 2 ANK repeats.
    Contains 1 Arf-GAP domain.
    Contains 1 PH domain.
  • Domain

    The PH domain mediates AP-3 binding.
  • Post-translational
    modifications

    Phosphorylated on tyrosines.
  • Cellular localization

    Cytoplasm. Associates with the endocytic compartment.
  • Information by UniProt

Images

  • 12.5% SDS-PAGE, stained with Coomassie Blue showing ab131978.

References

ab131978 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab131978.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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