Overview

  • Product name

    Recombinant Human AGBL4 protein
  • Protein length

    Protein fragment

Description

  • Nature

    Recombinant
  • Source

    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species

      Human
    • Molecular weight

      15 kDa
    • Amino acids

      294 to 422
    • Tags

      His-DHFR tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab127321 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form

    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20ºC.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • Reconstitution
    Reconstitute with water to desired concentration

General Info

  • Alternative names

    • AGBL4
    • ATP/GTP binding protein like 4
    • ATP/GTP-binding protein-like 4
    • CBPC6_HUMAN
    • CCP6
    • Cytosolic carboxypeptidase 6
    • FLJ14442
    see all
  • Function

    Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5.
  • Sequence similarities

    Belongs to the peptidase M14 family.
  • Cellular localization

    Cytoplasm > cytosol.
  • Information by UniProt

References

ab127321 has not yet been referenced specifically in any publications.

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