Recombinant human AK 1 protein (ab167983)

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Description

  • Product name

    Recombinant human AK 1 protein
    See all AK 1 proteins and peptides

  • Biological activity

    Specific activity: > 6.0 units/ml. One unit will convert 2.0 µmoles of ADP to ATP + AMP per minute at pH 7.5 at 25C.

  • Purity

    > 95 % SDS-PAGE.

  • Expression system

    Escherichia coli

  • Accession

    P00568

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MGSSHHHHHHSSGLVPRGSHMEEKLKKTKIIFVVGGPGSGKGTQCEKIVQ KYGYTHLSTGDLLRSEVSSGSARGKKLSEIMEKGQLVPLETVLDMLRDAM VAKVNTSKGFLIDGYPREVQQGEEFERRIGQPTLLLYVDAGPETMTQRLL KRGETSGRVDDNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVD SVFSQVCTHLDALK

    • Predicted molecular weight

      24 kDa including tags

    • Amino acids

      1 to 194

    • Tags

      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab167983 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

  • Form

    Liquid

  • Additional notes

    Previously labelled as Adenylate Kinase 1. 

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.32% Tris HCl, 10% Glycerol

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names

    • Adenylate kinase 1
    • Adenylate kinase isoenzyme 1
    • Adenylate kinase soluble
    • AK 1
    • Ak1
    • ATP AMP transphosphorylase
    • ATP-AMP transphosphorylase 1
    • KAD1
    • KAD1_HUMAN
    • Myokinase
    see all

  • Function

    Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Small ubiquitous enzyme involved in energy metabolism and nucleotide synthesis that is essential for maintenance and cell growth.

  • Involvement in disease

    Defects in AK1 are the cause of hemolytic anemia due to adenylate kinase deficiency [MIM:612631].

  • Sequence similarities

    Belongs to the adenylate kinase family.

  • Cellular localization

    Cytoplasm.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant human AK 1 protein (ab167983)
    SDS-PAGE - Recombinant human AK 1 protein (ab167983)
    15% SDS PAGE analysis of ab167983 at 3 µg.

References

ab167983 has not yet been referenced specifically in any publications.

Publishing research using ab167983? Please let us know so that we can cite the reference in this datasheet.

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