Recombinant human AKR1B10 protein (ab168014)
- Datasheet
- References
- Protocols
Overview
-
Product nameRecombinant human AKR1B10 protein
See all AKR1B10 proteins and peptides -
Protein lengthFull length protein
Description
-
NatureRecombinant
-
SourceEscherichia coli
-
Amino Acid Sequence
-
Accession
-
SpeciesHuman
-
SequenceMATFVELSTK AKMPIVGLGT WKSPLGKVKE AVKVAIDAGY RHIDCAYVYQ NEHEVGEAIQ EKIQEKAVKR EDLFIVSKLW PTFFERPLVR KAFEKTLKDL KLSYLDVYLI HWPQGFKSGD DLFPKDDKGN AIGGKATFLD AWEAMEELVD EGLVKALGVS NFSHFQIEKL LNKPGLKYKP VTNQVECHPY LTQEKLIQYC HSKGITVTAY SPLGSPDRPW AKPEDPSLLE DPKIKEIAAK HKKTAAQVLI RFHIQRNVIV IPKSVTPARI VENIQVFDFK LSDEEMATIL SFNRNWRACN VLQSSHLEDY PFDAEY
-
Molecular weight36 kDa
-
Amino acids1 to 316
-
Associated products
-
Related Products
Specifications
Our Abpromise guarantee covers the use of ab168014 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
Biological activity
The specific activity of AKR1B10 with 5 mM glyceraldehyde is approximately ~100 mU/mg. (Specific activity is calculated by the decrease of absorption at 340 nm in presence of 2-10 µg AKR1B10, 5mM glyceraldehyde, 200 µM NADPH in 0.1 M sodium phosphate buffer, pH 7.5).
-
Applications
SDS-PAGE
Functional Studies
-
Purity>90% by SDS-PAGE.
-
FormLiquid
-
Additional notesCentrifuge the vial prior to opening
-
Concentration information loading...
Preparation and Storage
-
Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: Tris HCl, 50% GlycerolThis product is an active protein and may elicit a biological response in vivo, handle with caution.
General Info
-
Alternative names
- AK1BA_HUMAN
- AKR1B10
- AKR1B11
see all -
FunctionActs as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.
-
Tissue specificityFound in many tissues. Highly expressed in small intestine, colon and adrenal gland.
-
Sequence similaritiesBelongs to the aldo/keto reductase family.
-
Cellular localizationLysosome. Secreted. Secreted through a lysosome-mediated non-classical pathway.
- Information by UniProt
Images
-
SDS-PAGE - Recombinant human AKR1B10 protein (ab168014)15% SDS-PAGE analysis of 3 µg ab168014.
Datasheets and documents
References
ab168014 has not yet been referenced specifically in any publications.
